Acokanthera schimperi (Arrow-Poison Tree)

Traditional uses

Africa

• Poison(Arrow)

Chemicals

Wood

• ACOLONGIFLOROSIDE
• ACOSCHIMPEROXIDES
• OUABAIN — 2000

Seed

• ACOLONGIFLOROSIDE-G — 37
• ACOLONGIFLOROSIDE-H-ACETATE — 240
• ACOVENOSIDE-A — 3000 to 17000
• ACOLONGIFLOROSIDE-H — 9800
• OUABAIN — 1000 to 5000

Activities

1. Antiarrhythmic — 1 compounds; OUABAIN
2. Anticarcinomic — 1 compounds; toxic activity; ACOVENOSIDE-A
3. Antiviral — 1 compounds; OUABAIN
4. Cardioactive — 1 compounds; toxic activity; ACOVENOSIDE-A
5. Cardiotonic — 1 compounds; toxic activity; OUABAIN
6. Diuretic — 1 compounds; OUABAIN
7. Emetic — 1 compounds; OUABAIN
8. Memorilytic — 1 compounds; OUABAIN

Toxic compounds

• ACOVENOSIDE-A — Anticarcinomic; Seed; ED50=31 ppb
• ACOVENOSIDE-A — Cardioactive; Seed
• OUABAIN — Cardiotonic; Seed; 100 ug/ivn/man/hr/up to 1 mg/day
• OUABAIN — Cardiotonic; Wood; 100 ug/ivn/man/hr/up to 1 mg/day