Cinchona officinalis (Lojabark)

Traditional uses

Elsewhere

  • Amebiasis
  • Bactericide
  • Cold
  • Contraceptive
  • Flu
  • Malaria
  • Neuralgia
  • Pertussis
  • Piles
  • Pinworms
  • Pneumonia
  • Schizonticide
  • Sciatica
  • Septicemia
  • Stomachic
  • Tonic
  • Typhoid
  • Varicosity
  • Uterotonic
  • Anesthetic
  • Carditis
  • Dysentery
  • Insecticide
  • Lumbago
  • Neuritis
  • Repellant(Insect)

Turkey

  • Antiseptic
  • Astringent
  • Fever
  • Nalaria
  • Tonic

Mexico

  • Antiseptic
  • Astringent
  • Malaria
  • Tonic

China

  • Hangover

Italy

  • Tumor(Glands)

Chemicals

Bark

  • CINCHONINE
  • HYDROQUINIDINE
  • QUININE
  • CINCHONIDINE
  • QUINIDINE
  • TANNIN

Leaf

  • AVICULARIN
  • 3-ALPHA,17-BETA-CINCHOPHYLLINE
  • 3-BETA,17-BETA-CINCHOPHYLLINE

Activities

  1. Pesticide — 8 compounds; 3-ALPHA,17-BETA-CINCHOPHYLLINE, 3-BETA,17-BETA-CINCHOPHYLLINE, AVICULARIN, CINCHONIDINE, CINCHONINE, HYDROQUINIDINE, QUININE, TANNIN
  2. Antimalarial — 5 compounds; CINCHONIDINE, CINCHONINE, HYDROQUINIDINE, QUINIDINE, QUININE
  3. Amebicide — 4 compounds; 3-ALPHA,17-BETA-CINCHOPHYLLINE, 3-BETA,17-BETA-CINCHOPHYLLINE, QUINIDINE, QUININE
  4. Antipyretic — 4 compounds; CINCHONIDINE, CINCHONINE, QUINIDINE, QUININE
  5. Cytotoxic — 3 compounds; toxic activity; 3-ALPHA,17-BETA-CINCHOPHYLLINE, 3-BETA,17-BETA-CINCHOPHYLLINE, QUININE
  6. MDR-Inhibitor — 3 compounds; CINCHONINE, QUINIDINE, QUININE
  7. Abortifacient — 2 compounds; toxic activity; QUINIDINE, QUININE
  8. Allergenic — 2 compounds; toxic activity; QUINIDINE, QUININE
  9. Analgesic — 2 compounds; QUINIDINE, QUININE
  10. Antiarrhythmic — 2 compounds; HYDROQUINIDINE, QUINIDINE
  11. Antibacterial — 2 compounds; QUININE, TANNIN
  12. Antidysenteric — 2 compounds; QUININE, TANNIN
  13. Antitumor — 2 compounds; QUINIDINE, TANNIN
  14. Antiviral — 2 compounds; CINCHONIDINE, TANNIN
  15. Cardiodepressant — 2 compounds; toxic activity; QUINIDINE, QUININE
  16. Dermatitigenic — 2 compounds; toxic activity; QUINIDINE, QUININE
  17. Immunosuppressant — 2 compounds; QUINIDINE, TANNIN
  18. Oxytocic — 2 compounds; QUINIDINE, QUININE
  19. Aldose-Reductase-Inhibitor — 1 compounds; AVICULARIN
  20. Anesthetic — 1 compounds; QUININE
  21. Anthelmintic — 1 compounds; TANNIN
  22. Antiaggregant — 1 compounds; CINCHONINE
  23. Antibiotic — 1 compounds; AVICULARIN
  24. Anticancer — 1 compounds; TANNIN
  25. Anticariogenic — 1 compounds; TANNIN
  26. Anticholinergic — 1 compounds; QUINIDINE
  27. Antidiarrheic — 1 compounds; TANNIN
  28. Antifeedant — 1 compounds; QUININE
  29. Antifibrillary — 1 compounds; QUININE
  30. Antiflu — 1 compounds; CINCHONIDINE
  31. Antihemorrhoidal — 1 compounds; QUININE
  32. Antihepatotoxic — 1 compounds; toxic activity; TANNIN
  33. Antiherpetic — 1 compounds; CINCHONIDINE
  34. Antihiccup — 1 compounds; QUINIDINE
  35. AntiHIV — 1 compounds; TANNIN
  36. Antihypertensive — 1 compounds; TANNIN
  37. Antilipolytic — 1 compounds; TANNIN
  38. Antilumbagic — 1 compounds; QUININE
  39. Antimutagenic — 1 compounds; toxic activity; TANNIN
  40. Antinephritic — 1 compounds; TANNIN
  41. Antineuralgic — 1 compounds; QUININE
  42. Antineuritic — 1 compounds; QUININE
  43. Antiophidic — 1 compounds; TANNIN
  44. Antioxidant — 1 compounds; TANNIN
  45. Antiradicular — 1 compounds; TANNIN
  46. Antirenitic — 1 compounds; TANNIN
  47. Antisciatic — 1 compounds; QUININE
  48. Antitachycardic — 1 compounds; QUINIDINE
  49. Antitrypanosomic — 1 compounds; QUININE
  50. Antitumor-Promoter — 1 compounds; TANNIN
  51. Antiulcer — 1 compounds; TANNIN
  52. Antiyeast — 1 compounds; QUININE
  53. Apertif — 1 compounds; QUININE
  54. Astringent — 1 compounds; QUININE
  55. Cancer-Preventive — 1 compounds; TANNIN
  56. Carcinogenic — 1 compounds; toxic activity; TANNIN
  57. Chelator — 1 compounds; TANNIN
  58. Cyclooxygenase-Activator — 1 compounds; AVICULARIN
  59. Cyclooxygenase-Inhibitor — 1 compounds; TANNIN
  60. Diuretic — 1 compounds; AVICULARIN
  61. Emetic — 1 compounds; QUINIDINE
  62. FLavor — 1 compounds; QUININE
  63. Glucosyl-Transferase-Inhibitor — 1 compounds; TANNIN
  64. Hemolytic — 1 compounds; QUINIDINE
  65. Hepatoprotective — 1 compounds; toxic activity; TANNIN
  66. Hypotensive — 1 compounds; QUINIDINE
  67. Laxative — 1 compounds; QUINIDINE
  68. Lipoxygenase-Inhibitor — 1 compounds; TANNIN
  69. MAO-Inhibitor — 1 compounds; TANNIN
  70. Myorelaxant — 1 compounds; QUINIDINE
  71. Ornithine-Decarboxylase-Inhibitor — 1 compounds; TANNIN
  72. PAF-Inhibitor — 1 compounds; CINCHONINE
  73. Phototoxic — 1 compounds; toxic activity; QUININE
  74. Protisticide — 1 compounds; QUININE
  75. Psychotropic — 1 compounds; TANNIN
  76. Spermicide — 1 compounds; QUININE
  77. Stomachic — 1 compounds; QUININE
  78. Tissue-Thromboplastin-Inhibitor — 1 compounds; AVICULARIN
  79. Trypanocide — 1 compounds; QUININE
  80. Xanthine-Oxidase-Inhibitor — 1 compounds; TANNIN

Toxic compounds

  • 3-ALPHA,17-BETA-CINCHOPHYLLINE — Cytotoxic; Leaf; IC50=0.4 ug/ml
  • 3-BETA,17-BETA-CINCHOPHYLLINE — Cytotoxic; Leaf; IC50=2.24 ug/ml
  • QUINIDINE — Abortifacient; Bark
  • QUINIDINE — Allergenic; Bark
  • QUINIDINE — Cardiodepressant; Bark
  • QUINIDINE — Dermatitigenic; Bark
  • QUININE — Abortifacient; Bark
  • QUININE — Allergenic; Bark
  • QUININE — Cardiodepressant; Bark
  • QUININE — Cytotoxic; Bark; IC50=183 ug/ml
  • QUININE — Dermatitigenic; Bark
  • QUININE — Phototoxic; Bark
  • TANNIN — Antihepatotoxic; Bark
  • TANNIN — Antimutagenic; Bark
  • TANNIN — Carcinogenic; Bark
  • TANNIN — Hepatoprotective; Bark