Colchicum autumnale (Autumn Crocus)

Traditional uses

Turkey

  • Alterative
  • Diuretic
  • Laxative
  • Poison
  • Rheumatism
  • Sudorific
  • Homeopathy

Greece

  • Leukemia

Elsewhere

  • Rheumatism
  • Gout
  • Sedative

Europe

  • Cancer
  • Fatality

Germany

  • Corn

Spain

  • Poison

Chemicals

Plant

  • O-ACETYLCOLCHICEINE
  • N-ACETYLDEMECOLCINE
  • 2-ACETYL-2-DEMETHYLCOLCHICINE
  • AUTUMNALINE
  • CHELIDONIC-ACID
  • COLCHIFOLINE
  • DEMECOLCEINE
  • DEMECOLCINE
  • 3-ACETYL-3-DEMETHYLCOLCHICINE
  • SALICYLIC-ACID

Tuber

  • APIGENIN
  • BENZOIC-ACID
  • COLCHICENE
  • COLCHICERINE
  • N-DEACETYL-N-METHYLCOLCHICINE
  • 3-DEMETHYLCOLCHICINE
  • O-DEMETHYL-N-DEACETYLCOLCHICINE
  • 3-DEMETHYL-BETA-LUMICOLCHICINE
  • 3-DESMETHYLDEMECOLCINE
  • 2-DESMETHYLDEACETYLCOLCHICINE
  • N-FORMYL-N-DEACETYLCOLCHICINE
  • 2-HYDROXY-6-METHOXYBENZOIC-ACID
  • GAMMA-LUMICOLCHICINE
  • 6-METHOXY-SALICYLIC-ACID
  • 3-METHYL-COLCHICINE
  • ALPHA-LUMICOLCHICINE
  • COLCHAMINE
  • 2-DEMETHYLCOLCHICINE
  • 3-DEMETHYL-GAMMA-LUMICOLCHICINE
  • BETA-LUMICOLCHICINE
  • N-METHYLDESACETYLCOLCHICINE
  • STARCH — 210000
  • COLCHICINE — 800 to 12300

Activities

  1. Pesticide — 5 compounds; APIGENIN, BENZOIC-ACID, COLCHAMINE, COLCHICINE, SALICYLIC-ACID
  2. Antibacterial — 4 compounds; APIGENIN, BENZOIC-ACID, COLCHICINE, SALICYLIC-ACID
  3. Antiinflammatory — 3 compounds; APIGENIN, COLCHICINE, SALICYLIC-ACID
  4. Antileukemic — 3 compounds; APIGENIN, COLCHICINE, DEMECOLCINE
  5. Antipodagric — 3 compounds; COLCHICINE, DEMECOLCINE, SALICYLIC-ACID
  6. Antipyretic — 3 compounds; BENZOIC-ACID, COLCHICINE, SALICYLIC-ACID
  7. Antitubulin — 3 compounds; 2-DEMETHYLCOLCHICINE, COLCHICINE, DEMECOLCINE
  8. Antitumor — 3 compounds; APIGENIN, DEMECOLCINE, SALICYLIC-ACID
  9. Antiarthritic — 2 compounds; COLCHICINE, SALICYLIC-ACID
  10. Antidermatitic — 2 compounds; toxic activity; APIGENIN, COLCHICINE
  11. Antiherpetic — 2 compounds; APIGENIN, COLCHICINE
  12. AntiHIV — 2 compounds; APIGENIN, COLCHICINE
  13. Antimelanomic — 2 compounds; APIGENIN, COLCHICINE
  14. Antimitotic — 2 compounds; COLCHICINE, DEMECOLCINE
  15. Antioxidant — 2 compounds; APIGENIN, SALICYLIC-ACID
  16. Antipsoriac — 2 compounds; COLCHICINE, SALICYLIC-ACID
  17. Antirheumatic — 2 compounds; COLCHICINE, SALICYLIC-ACID
  18. Antiseptic — 2 compounds; BENZOIC-ACID, SALICYLIC-ACID
  19. Antitumor (Breast) — 2 compounds; APIGENIN, COLCHICINE
  20. Antitumor (Lung) — 2 compounds; APIGENIN, COLCHICINE
  21. Antiviral — 2 compounds; APIGENIN, COLCHAMINE
  22. Cancer-Preventive — 2 compounds; APIGENIN, SALICYLIC-ACID
  23. Choleretic — 2 compounds; APIGENIN, BENZOIC-ACID
  24. COX-2-Inhibitor — 2 compounds; APIGENIN, SALICYLIC-ACID
  25. Cyclooxygenase-Inhibitor — 2 compounds; APIGENIN, SALICYLIC-ACID
  26. Cytotoxic — 2 compounds; toxic activity; APIGENIN, COLCHICINE
  27. Fungicide — 2 compounds; BENZOIC-ACID, SALICYLIC-ACID
  28. Insectifuge — 2 compounds; BENZOIC-ACID, SALICYLIC-ACID
  29. Irritant — 2 compounds; toxic activity; CHELIDONIC-ACID, COLCHICINE
  30. Uricosuric — 2 compounds; BENZOIC-ACID, COLCHICINE
  31. 11B-HSD-Inhibitor — 1 compounds; APIGENIN
  32. Absorbent — 1 compounds; STARCH
  33. Aldose-Reductase-Inhibitor — 1 compounds; SALICYLIC-ACID
  34. Allergenic — 1 compounds; toxic activity; BENZOIC-ACID
  35. Analgesic — 1 compounds; SALICYLIC-ACID
  36. Anesthetic — 1 compounds; BENZOIC-ACID
  37. AntiADD — 1 compounds; APIGENIN
  38. Antiaflatoxin — 1 compounds; APIGENIN
  39. Antiaggregant — 1 compounds; APIGENIN
  40. Antiaging — 1 compounds; APIGENIN
  41. Antiallergic — 1 compounds; APIGENIN
  42. Antiamyloidosic — 1 compounds; COLCHICINE
  43. Antiangiogenic — 1 compounds; APIGENIN
  44. Antiarrhythmic — 1 compounds; APIGENIN
  45. AntiBehcet's — 1 compounds; COLCHICINE
  46. Anticancer (Lung) — 1 compounds; APIGENIN
  47. Anticirrhotic — 1 compounds; COLCHICINE
  48. Anticomplementary — 1 compounds; APIGENIN
  49. Antidandruff — 1 compounds; SALICYLIC-ACID
  50. Antidermatotic — 1 compounds; SALICYLIC-ACID
  51. Antidote (Iodine) — 1 compounds; STARCH
  52. Antieczemic — 1 compounds; SALICYLIC-ACID
  53. Antierythemic — 1 compounds; COLCHICINE
  54. Antiestrogenic — 1 compounds; APIGENIN
  55. Antiflu — 1 compounds; COLCHAMINE
  56. Antihistaminic — 1 compounds; APIGENIN
  57. Antiichthyosic — 1 compounds; SALICYLIC-ACID
  58. Antimalarial — 1 compounds; COLCHICINE
  59. Antimeningitic — 1 compounds; COLCHICINE
  60. Antimetastatic — 1 compounds; APIGENIN
  61. Antimutagenic — 1 compounds; toxic activity; APIGENIN
  62. Antinesidioblastosic — 1 compounds; STARCH
  63. Antineuralgic — 1 compounds; SALICYLIC-ACID
  64. Antioncychomycotic — 1 compounds; SALICYLIC-ACID
  65. Antiotitic — 1 compounds; BENZOIC-ACID
  66. AntiPaget's — 1 compounds; COLCHICINE
  67. Antipericarditis — 1 compounds; COLCHICINE
  68. Antiperiodic — 1 compounds; SALICYLIC-ACID
  69. Antiperistaltic — 1 compounds; APIGENIN
  70. Antipolyserositic — 1 compounds; COLCHICINE
  71. Antiproliferant — 1 compounds; APIGENIN
  72. Antisalmonella — 1 compounds; BENZOIC-ACID
  73. Antisarcomic — 1 compounds; COLCHICINE
  74. Antiseborrheic — 1 compounds; SALICYLIC-ACID
  75. Antispasmodic — 1 compounds; APIGENIN
  76. Antistress — 1 compounds; APIGENIN
  77. Antithrombocytopenic — 1 compounds; COLCHICINE
  78. Antithyroid — 1 compounds; APIGENIN
  79. Antitrypanosomic — 1 compounds; COLCHICINE
  80. Antitumor (Colon) — 1 compounds; COLCHICINE
  81. Antitumor (Skin) — 1 compounds; APIGENIN
  82. Antitympanitic — 1 compounds; SALICYLIC-ACID
  83. Antivasculitic — 1 compounds; COLCHICINE
  84. Antiwart — 1 compounds; CHELIDONIC-ACID
  85. Antiyeast — 1 compounds; BENZOIC-ACID
  86. Anxiolytic — 1 compounds; APIGENIN
  87. Apoptotic — 1 compounds; APIGENIN
  88. Aromatase-Inhibitor — 1 compounds; APIGENIN
  89. Beta-Glucuronidase-Inhibitor — 1 compounds; APIGENIN
  90. Calcium-Antagonist? — 1 compounds; APIGENIN
  91. Carcinogenic — 1 compounds; toxic activity; COLCHICINE
  92. Cardioactive — 1 compounds; toxic activity; COLCHICINE
  93. CNS-Depressant — 1 compounds; APIGENIN
  94. CNS-Paralytic — 1 compounds; toxic activity; COLCHICINE
  95. CNS-Stimulant — 1 compounds; COLCHICINE
  96. Comedolytic — 1 compounds; SALICYLIC-ACID
  97. COX-1-Inhibitor — 1 compounds; APIGENIN
  98. Cytochrome-P450-1A1-Inhibitor — 1 compounds; APIGENIN
  99. Deiodinase-Inhibitor — 1 compounds; APIGENIN
  100. Dermatitigenic — 1 compounds; toxic activity; SALICYLIC-ACID
  101. Differentiator — 1 compounds; APIGENIN
  102. Diuretic — 1 compounds; APIGENIN
  103. DNA-Protective — 1 compounds; APIGENIN
  104. Emetic — 1 compounds; COLCHICINE
  105. Emollient — 1 compounds; STARCH
  106. Estrogenic — 1 compounds; APIGENIN
  107. Expectorant — 1 compounds; BENZOIC-ACID
  108. FLavor — 1 compounds; BENZOIC-ACID
  109. Hepatoprotective — 1 compounds; toxic activity; COLCHICINE
  110. HIF-1alpha-Inhibitor — 1 compounds; APIGENIN
  111. Hyaluronidase-Inhibitor — 1 compounds; APIGENIN
  112. Hypertensive — 1 compounds; COLCHICINE
  113. Hypoglycemic — 1 compounds; SALICYLIC-ACID
  114. Hypotensive — 1 compounds; APIGENIN
  115. ICAM-1-Inhibitor — 1 compounds; APIGENIN
  116. IKK-Inhibitor — 1 compounds; APIGENIN
  117. iNOS-Inhibitor — 1 compounds; APIGENIN
  118. Inotropic — 1 compounds; APIGENIN
  119. Interleukin-6-Inhibitor — 1 compounds; APIGENIN
  120. Keratolytic — 1 compounds; SALICYLIC-ACID
  121. MAO-Inhibitor — 1 compounds; APIGENIN
  122. MAPK-Inhibitor — 1 compounds; APIGENIN
  123. Marrow-Suppresant — 1 compounds; DEMECOLCINE
  124. MDR-Inhibitor — 1 compounds; DEMECOLCINE
  125. Musculotropic — 1 compounds; APIGENIN
  126. Mutagenic — 1 compounds; toxic activity; APIGENIN
  127. Myorelaxant — 1 compounds; APIGENIN
  128. NADH-Oxidase-Inhibitor — 1 compounds; APIGENIN
  129. Neoplastic — 1 compounds; COLCHAMINE
  130. NF-kB-Inhibitor — 1 compounds; APIGENIN
  131. NO-Synthase-Inhibitor — 1 compounds; APIGENIN
  132. Nodulation-Signal — 1 compounds; APIGENIN
  133. Ornithine-Decarboxylase-Inhibitor — 1 compounds; APIGENIN
  134. P21-Inducer — 1 compounds; APIGENIN
  135. Phytoalexin — 1 compounds; BENZOIC-ACID
  136. PKC-Inhibitor — 1 compounds; APIGENIN
  137. Polyamine-Synthesis-Inhibitor — 1 compounds; APIGENIN
  138. Poultice — 1 compounds; STARCH
  139. Progestational — 1 compounds; APIGENIN
  140. Protein-Kinase-C-Inhibitor — 1 compounds; APIGENIN
  141. PTK-Inhibitor — 1 compounds; APIGENIN
  142. Purgative — 1 compounds; COLCHICINE
  143. Quinone-Reductase-Inducer — 1 compounds; APIGENIN
  144. Radioprotective — 1 compounds; APIGENIN
  145. Respiradepressant — 1 compounds; COLCHICINE
  146. Sedative — 1 compounds; APIGENIN
  147. Sunscreen — 1 compounds; APIGENIN
  148. Sympathomimetic — 1 compounds; COLCHICINE
  149. Teratogenic — 1 compounds; toxic activity; COLCHAMINE
  150. Thermogenic — 1 compounds; SALICYLIC-ACID
  151. Tineacide — 1 compounds; SALICYLIC-ACID
  152. TNF-alpha-Inhibitor — 1 compounds; APIGENIN
  153. Topoisomerase-I-Inhibitor — 1 compounds; APIGENIN
  154. Topoisomerase-II-Inhibitor — 1 compounds; APIGENIN
  155. Tyrosinase-Inhibitor — 1 compounds; BENZOIC-ACID
  156. Ulcerogenic — 1 compounds; SALICYLIC-ACID
  157. Uterotrophic — 1 compounds; APIGENIN
  158. Vasodilator — 1 compounds; APIGENIN
  159. VEGF-Inhibitor — 1 compounds; APIGENIN
  160. Vulnerary — 1 compounds; BENZOIC-ACID
  161. Xanthine-Oxidase-Inhibitor — 1 compounds; APIGENIN

Toxic compounds

  • APIGENIN — Antidermatitic; Tuber
  • APIGENIN — Antimutagenic; Tuber; ID50=10-40 nM
  • APIGENIN — Cytotoxic; Tuber; IC88=10 ug/ml
  • APIGENIN — Mutagenic; Tuber
  • BENZOIC-ACID — Allergenic; Tuber
  • CHELIDONIC-ACID — Irritant; Plant
  • COLCHAMINE — Teratogenic; Tuber
  • COLCHICINE — Antidermatitic; Tuber
  • COLCHICINE — Carcinogenic; Tuber
  • COLCHICINE — Cardioactive; Tuber; 15 mg/kg scu rbt
  • COLCHICINE — CNS-Paralytic; Tuber
  • COLCHICINE — Cytotoxic; Tuber; IC50=0.018 uM
  • COLCHICINE — Hepatoprotective; Tuber
  • COLCHICINE — Irritant; Tuber
  • SALICYLIC-ACID — Dermatitigenic; Plant