Daphne genkwa (Yuan Hua)

Traditional uses

China

  • Antidote(Mushroom)
  • Antitussive
  • Ascites
  • Cancer
  • Cough
  • Decoagulant
  • Diuretic
  • Edema
  • Malaria
  • Tonic
  • Vesicant
  • Wound
  • Fever
  • Piscicide
  • Bubo
  • Favus
  • Poison
  • Purgative
  • Skin
  • Sore
  • Trauma
  • Bruise
  • Uterus

Elsewhere

  • Antitussive

Chinese

  • Anthelminthic

Allelsewhere

  • Antiphlogistic

Chemicals

Flower

  • APIGENIN
  • GENKWANIN
  • GENKWADAPHNIN
  • HYDROXYGENKWANIN
  • KAEMPFEROL3-O-BETA-D-(6'-P-COUMAROYL)GLUCOPYRANOSIDE
  • LUTEOLIN
  • LUTEOLIN-7-METHYL-ETHER
  • BENZOIC-ACID
  • BETA-SITOSTEROL

Root

  • GENKWANIN-5-GLYCOSIDE
  • YUANHUADINE
  • YUANHUAFINE
  • YUANHUATINE
  • XYLOSE
  • YUANHUACINE
  • GLUCOSE
  • YUENKANIN — 9000

Plant

  • YUANHUAPINE
  • 3'-HYDROXYGENKWANIN

Activities

  1. Antibacterial — 5 compounds; APIGENIN, BENZOIC-ACID, BETA-SITOSTEROL, GENKWANIN, LUTEOLIN
  2. Antileukemic — 5 compounds; APIGENIN, BETA-SITOSTEROL, GENKWADAPHNIN, LUTEOLIN, YUANHUACINE
  3. Pesticide — 5 compounds; APIGENIN, BENZOIC-ACID, BETA-SITOSTEROL, GENKWANIN, LUTEOLIN
  4. Abortifacient — 4 compounds; toxic activity; YUANHUACINE, YUANHUADINE, YUANHUAFINE, YUANHUATINE
  5. Antitumor — 4 compounds; APIGENIN, LUTEOLIN, YUANHUADINE, YUANHUAFINE
  6. Antiestrogenic — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  7. Antiinflammatory — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  8. Antimutagenic — 3 compounds; toxic activity; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  9. Antioxidant — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  10. Antitumor (Lung) — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  11. Antiviral — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  12. Apoptotic — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  13. Cancer-Preventive — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  14. Choleretic — 3 compounds; APIGENIN, BENZOIC-ACID, LUTEOLIN
  15. Estrogenic — 3 compounds; APIGENIN, BETA-SITOSTEROL, LUTEOLIN
  16. Pyrogenic — 3 compounds; YUANHUACINE, YUANHUADINE, YUANHUAFINE
  17. Antiallergic — 2 compounds; APIGENIN, LUTEOLIN
  18. Antiangiogenic — 2 compounds; APIGENIN, LUTEOLIN
  19. Anticancer (Lung) — 2 compounds; APIGENIN, BETA-SITOSTEROL
  20. Anticomplementary — 2 compounds; APIGENIN, LUTEOLIN
  21. Antiedemic — 2 compounds; BETA-SITOSTEROL, GLUCOSE
  22. Antifeedant — 2 compounds; BETA-SITOSTEROL, LUTEOLIN
  23. Antiherpetic — 2 compounds; APIGENIN, LUTEOLIN
  24. Antihistaminic — 2 compounds; APIGENIN, LUTEOLIN
  25. AntiHIV — 2 compounds; APIGENIN, LUTEOLIN
  26. Antilymphomic — 2 compounds; BETA-SITOSTEROL, LUTEOLIN
  27. Antimelanomic — 2 compounds; APIGENIN, LUTEOLIN
  28. Antiproliferant — 2 compounds; APIGENIN, LUTEOLIN
  29. Antipyretic — 2 compounds; BENZOIC-ACID, BETA-SITOSTEROL
  30. Antispasmodic — 2 compounds; APIGENIN, LUTEOLIN
  31. Antitumor (Breast) — 2 compounds; APIGENIN, BETA-SITOSTEROL
  32. Antitumor (Skin) — 2 compounds; APIGENIN, LUTEOLIN
  33. Antitussive — 2 compounds; HYDROXYGENKWANIN, LUTEOLIN
  34. Aromatase-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  35. Beta-Glucuronidase-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  36. Cytotoxic — 2 compounds; toxic activity; APIGENIN, LUTEOLIN
  37. Deiodinase-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  38. Differentiator — 2 compounds; APIGENIN, LUTEOLIN
  39. Diuretic — 2 compounds; APIGENIN, LUTEOLIN
  40. Expectorant — 2 compounds; BENZOIC-ACID, HYDROXYGENKWANIN
  41. Hepatoprotective — 2 compounds; toxic activity; BETA-SITOSTEROL, LUTEOLIN
  42. Hyaluronidase-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  43. Hypocholesterolemic — 2 compounds; BETA-SITOSTEROL, LUTEOLIN
  44. ICAM-1-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  45. IKK-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  46. iNOS-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  47. MAPK-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  48. Myorelaxant — 2 compounds; APIGENIN, LUTEOLIN
  49. NF-kB-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  50. Protein-Kinase-C-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  51. PTK-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  52. TNF-alpha-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  53. Topoisomerase-I-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  54. Vasodilator — 2 compounds; APIGENIN, LUTEOLIN
  55. VEGF-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  56. Xanthine-Oxidase-Inhibitor — 2 compounds; APIGENIN, LUTEOLIN
  57. 11B-HSD-Inhibitor — 1 compounds; APIGENIN
  58. Acetylcholinergic — 1 compounds; GLUCOSE
  59. Aldose-Reductase-Inhibitor — 1 compounds; LUTEOLIN
  60. Allergenic — 1 compounds; toxic activity; BENZOIC-ACID
  61. Androgenic — 1 compounds; BETA-SITOSTEROL
  62. Anesthetic — 1 compounds; BENZOIC-ACID
  63. Angiogenic — 1 compounds; BETA-SITOSTEROL
  64. Anorexic — 1 compounds; BETA-SITOSTEROL
  65. AntiADD — 1 compounds; APIGENIN
  66. Antiadenomic — 1 compounds; BETA-SITOSTEROL
  67. Antiaflatoxin — 1 compounds; APIGENIN
  68. Antiaggregant — 1 compounds; APIGENIN
  69. Antiaging — 1 compounds; APIGENIN
  70. Antiandrogenic — 1 compounds; BETA-SITOSTEROL
  71. Antiarrhythmic — 1 compounds; APIGENIN
  72. Antiatherogenic — 1 compounds; LUTEOLIN
  73. Anticancer (Breast) — 1 compounds; BETA-SITOSTEROL
  74. Anticancer (Cervix) — 1 compounds; BETA-SITOSTEROL
  75. Anticarcinogenic — 1 compounds; toxic activity; LUTEOLIN
  76. Anticarcinomic — 1 compounds; toxic activity; LUTEOLIN
  77. Anticataract — 1 compounds; LUTEOLIN
  78. Antidermatic — 1 compounds; toxic activity; LUTEOLIN
  79. Antidermatitic — 1 compounds; toxic activity; APIGENIN
  80. Antidiabetic — 1 compounds; XYLOSE
  81. Antifertility — 1 compounds; BETA-SITOSTEROL
  82. Antigonadotrophic — 1 compounds; BETA-SITOSTEROL
  83. Antihepatotoxic — 1 compounds; toxic activity; GLUCOSE
  84. Antihyperlipoproteinaemic — 1 compounds; BETA-SITOSTEROL
  85. Antiketotic — 1 compounds; GLUCOSE
  86. Antimetastatic — 1 compounds; APIGENIN
  87. Antinociceptive — 1 compounds; LUTEOLIN
  88. Antiophidic — 1 compounds; BETA-SITOSTEROL
  89. Antiotitic — 1 compounds; BENZOIC-ACID
  90. Antiperistaltic — 1 compounds; APIGENIN
  91. Antipolio — 1 compounds; LUTEOLIN
  92. Antiprogestational — 1 compounds; BETA-SITOSTEROL
  93. Antiprostaglandin — 1 compounds; BETA-SITOSTEROL
  94. Antiprostatadenomic — 1 compounds; BETA-SITOSTEROL
  95. Antiprostatitic — 1 compounds; BETA-SITOSTEROL
  96. Antisalmonella — 1 compounds; BENZOIC-ACID
  97. Antiseptic — 1 compounds; BENZOIC-ACID
  98. Antistress — 1 compounds; APIGENIN
  99. Antithyroid — 1 compounds; APIGENIN
  100. Antitumor (brain) — 1 compounds; LUTEOLIN
  101. Antitumor (Cervix) — 1 compounds; BETA-SITOSTEROL
  102. Antitumor (Colon) — 1 compounds; LUTEOLIN
  103. Antitumor (Kidney) — 1 compounds; LUTEOLIN
  104. Antitumor (Ovary) — 1 compounds; LUTEOLIN
  105. Antitumor (Pancreas) — 1 compounds; LUTEOLIN
  106. Antitumor (Stomach) — 1 compounds; LUTEOLIN
  107. Antitumor (Thyroid) — 1 compounds; LUTEOLIN
  108. Antivaricose — 1 compounds; GLUCOSE
  109. Antiyeast — 1 compounds; BENZOIC-ACID
  110. Anxiolytic — 1 compounds; APIGENIN
  111. Aphidifuge — 1 compounds; LUTEOLIN
  112. Artemicide — 1 compounds; BETA-SITOSTEROL
  113. Calcium-Antagonist — 1 compounds; LUTEOLIN
  114. Calcium-Antagonist? — 1 compounds; APIGENIN
  115. Candidicide — 1 compounds; BETA-SITOSTEROL
  116. Caspase-8-Inducer — 1 compounds; BETA-SITOSTEROL
  117. Chemopreventive — 1 compounds; LUTEOLIN
  118. CNS-Depressant — 1 compounds; APIGENIN
  119. COX-1-Inhibitor — 1 compounds; APIGENIN
  120. COX-2-Inhibitor — 1 compounds; APIGENIN
  121. Cyclooxygenase-Inhibitor — 1 compounds; APIGENIN
  122. Cytochrome-P450-1A1-Inhibitor — 1 compounds; APIGENIN
  123. Diagnostic — 1 compounds; XYLOSE
  124. DNA-Protective — 1 compounds; APIGENIN
  125. Dye — 1 compounds; XYLOSE
  126. Febrifuge — 1 compounds; BETA-SITOSTEROL
  127. FLavor — 1 compounds; BENZOIC-ACID
  128. Fungicide — 1 compounds; BENZOIC-ACID
  129. Gonadotrophic — 1 compounds; BETA-SITOSTEROL
  130. HIF-1alpha-Inhibitor — 1 compounds; APIGENIN
  131. Hyperglycemic — 1 compounds; GLUCOSE
  132. Hypoglycemic — 1 compounds; BETA-SITOSTEROL
  133. Hypolipidemic — 1 compounds; BETA-SITOSTEROL
  134. Hypotensive — 1 compounds; APIGENIN
  135. Inotropic — 1 compounds; APIGENIN
  136. Insectifuge — 1 compounds; BENZOIC-ACID
  137. Interleukin-6-Inhibitor — 1 compounds; APIGENIN
  138. Iodothyronine-Deiodinase-Inhibitor — 1 compounds; LUTEOLIN
  139. Lipoxygenase-Inhibitor — 1 compounds; LUTEOLIN
  140. MAO-Inhibitor — 1 compounds; APIGENIN
  141. Memory-Enhancer — 1 compounds; GLUCOSE
  142. Metalloproteinase-Inhibitor — 1 compounds; LUTEOLIN
  143. MMP-9-Inhibitor — 1 compounds; LUTEOLIN
  144. Musculotropic — 1 compounds; APIGENIN
  145. Mutagenic — 1 compounds; toxic activity; APIGENIN
  146. NADH-Oxidase-Inhibitor — 1 compounds; APIGENIN
  147. NEP-Inhibitor — 1 compounds; LUTEOLIN
  148. NO-Inhibitor — 1 compounds; LUTEOLIN
  149. NO-Synthase-Inhibitor — 1 compounds; APIGENIN
  150. Nodulation-Signal — 1 compounds; APIGENIN
  151. Ornithine-Decarboxylase-Inhibitor — 1 compounds; APIGENIN
  152. P21-Inducer — 1 compounds; APIGENIN
  153. Phytoalexin — 1 compounds; BENZOIC-ACID
  154. PKC-Inhibitor — 1 compounds; APIGENIN
  155. Polyamine-Synthesis-Inhibitor — 1 compounds; APIGENIN
  156. Progestational — 1 compounds; APIGENIN
  157. Proliferant — 1 compounds; LUTEOLIN
  158. Prostaglandin-Synthetase-Inhibitor — 1 compounds; LUTEOLIN
  159. Purgative — 1 compounds; GENKWANIN
  160. Quinone-Reductase-Inducer — 1 compounds; APIGENIN
  161. Radioprotective — 1 compounds; APIGENIN
  162. Sedative — 1 compounds; APIGENIN
  163. Spermicide — 1 compounds; BETA-SITOSTEROL
  164. Succinoxidase-Inhibitor — 1 compounds; LUTEOLIN
  165. Sunscreen — 1 compounds; APIGENIN
  166. Topoisomerase-II-Inhibitor — 1 compounds; APIGENIN
  167. Tyrosinase-Inhibitor — 1 compounds; BENZOIC-ACID
  168. Ubiquiot — 1 compounds; BETA-SITOSTEROL
  169. Ulcerogenic — 1 compounds; BETA-SITOSTEROL
  170. Uricosuric — 1 compounds; BENZOIC-ACID
  171. Uterocontractant — 1 compounds; YUANHUACINE
  172. Uterotrophic — 1 compounds; APIGENIN
  173. Vulnerary — 1 compounds; BENZOIC-ACID

Toxic compounds

  • APIGENIN — Antidermatitic; Flower
  • APIGENIN — Antimutagenic; Flower; ID50=10-40 nM
  • APIGENIN — Cytotoxic; Flower; IC88=10 ug/ml
  • APIGENIN — Mutagenic; Flower
  • BENZOIC-ACID — Allergenic; Flower
  • BETA-SITOSTEROL — Antimutagenic; Flower; 250 ug/ml
  • BETA-SITOSTEROL — Hepatoprotective; Flower
  • GLUCOSE — Antihepatotoxic; Root
  • LUTEOLIN — Anticarcinogenic; Flower
  • LUTEOLIN — Anticarcinomic; Flower
  • LUTEOLIN — Antidermatic; Flower
  • LUTEOLIN — Antimutagenic; Flower; ID50=2-5 nM
  • LUTEOLIN — Cytotoxic; Flower; 1-50 uM
  • LUTEOLIN — Hepatoprotective; Flower
  • YUANHUACINE — Abortifacient; Root
  • YUANHUADINE — Abortifacient; Root
  • YUANHUAFINE — Abortifacient; Root
  • YUANHUATINE — Abortifacient; Root