Daphne mezereum (Spurge Laurel)

Traditional uses

Turkey

  • Abortifacient
  • Alterative
  • Liniment
  • Poison
  • Purgative
  • Sudorific
  • Stimulant
  • Diuretic
  • Syphilis

US

  • Carcinogenic
  • Poison

Elsewhere

  • Diuretic
  • Sialogogue
  • Stimulant

Spain

  • Poison

Europe

  • Sclerosis(Uterus)

Chemicals

Fruit

  • COCOGNINIC-ACID
  • MEZEREIN — 1000
  • COCOGNINE
  • 6-METHOXY-7-HYDROXY-3,7'-DICOUMARYLETHER

Bark

  • DAPHNETOXIN
  • DAPHNORETIN
  • MALIC-ACID

Plant

  • DAPHNOPSIDE
  • BETA-SITOSTEROL
  • SUCROSE
  • UMBELLIFERTONE
  • HESPERIDIN
  • DAPHNIN
  • 12-HYDROXYDAPHNETOXIN

Seed

  • DAPHNETOXIN — 200
  • FAT — 60000 to 654000
  • PROTEIN — 75000 to 244000

Activities

  1. Antitumor — 4 compounds; 12-HYDROXYDAPHNETOXIN, DAPHNORETIN, MALIC-ACID, MEZEREIN
  2. Antioxidant — 3 compounds; BETA-SITOSTEROL, HESPERIDIN, SUCROSE
  3. Pesticide — 3 compounds; BETA-SITOSTEROL, HESPERIDIN, MALIC-ACID
  4. Antibacterial — 2 compounds; BETA-SITOSTEROL, MALIC-ACID
  5. Antiinflammatory — 2 compounds; BETA-SITOSTEROL, HESPERIDIN
  6. Antileukemic — 2 compounds; BETA-SITOSTEROL, MEZEREIN
  7. Antiprostaglandin — 2 compounds; BETA-SITOSTEROL, HESPERIDIN
  8. Antiviral — 2 compounds; BETA-SITOSTEROL, HESPERIDIN
  9. Hypolipidemic — 2 compounds; BETA-SITOSTEROL, HESPERIDIN
  10. Aggregant — 1 compounds; SUCROSE
  11. Analgesic — 1 compounds; HESPERIDIN
  12. Androgenic — 1 compounds; BETA-SITOSTEROL
  13. Angiogenic — 1 compounds; BETA-SITOSTEROL
  14. Anorexic — 1 compounds; BETA-SITOSTEROL
  15. Anti-LDL — 1 compounds; HESPERIDIN
  16. Antiadenomic — 1 compounds; BETA-SITOSTEROL
  17. Antiallergenic — 1 compounds; toxic activity; HESPERIDIN
  18. Antiandrogenic — 1 compounds; BETA-SITOSTEROL
  19. Antiatherosclerotic — 1 compounds; MALIC-ACID
  20. Antibradykinic — 1 compounds; HESPERIDIN
  21. Anticancer (Breast) — 1 compounds; BETA-SITOSTEROL
  22. Anticancer (Cervix) — 1 compounds; BETA-SITOSTEROL
  23. Anticancer (Lung) — 1 compounds; BETA-SITOSTEROL
  24. Anticapillary-Fragility — 1 compounds; HESPERIDIN
  25. Anticarcinomic — 1 compounds; toxic activity; DAPHNORETIN
  26. AntiDNA — 1 compounds; HESPERIDIN
  27. Antiedemic — 1 compounds; BETA-SITOSTEROL
  28. Antiestrogenic — 1 compounds; BETA-SITOSTEROL
  29. Antifeedant — 1 compounds; BETA-SITOSTEROL
  30. Antifertility — 1 compounds; BETA-SITOSTEROL
  31. Antifibromyalgic — 1 compounds; MALIC-ACID
  32. Antiflu — 1 compounds; HESPERIDIN
  33. Antigonadotrophic — 1 compounds; BETA-SITOSTEROL
  34. Antihiccup — 1 compounds; SUCROSE
  35. Antihistaminic — 1 compounds; HESPERIDIN
  36. Antihyperlipoproteinaemic — 1 compounds; BETA-SITOSTEROL
  37. Antileukotriene — 1 compounds; HESPERIDIN
  38. Antilymphomic — 1 compounds; BETA-SITOSTEROL
  39. Antimutagenic — 1 compounds; toxic activity; BETA-SITOSTEROL
  40. Antiophidic — 1 compounds; BETA-SITOSTEROL
  41. Antiophthalmic — 1 compounds; SUCROSE
  42. Antioxidant Synergist — 1 compounds; MALIC-ACID
  43. Antiprogestational — 1 compounds; BETA-SITOSTEROL
  44. Antiprostatadenomic — 1 compounds; BETA-SITOSTEROL
  45. Antiprostatitic — 1 compounds; BETA-SITOSTEROL
  46. Antipyretic — 1 compounds; BETA-SITOSTEROL
  47. AntiRNA — 1 compounds; HESPERIDIN
  48. Antiseborrheic — 1 compounds; MALIC-ACID
  49. Antiseptic — 1 compounds; MALIC-ACID
  50. Antistomatitic — 1 compounds; HESPERIDIN
  51. Antitriglyceride — 1 compounds; HESPERIDIN
  52. Antitubercular — 1 compounds; MALIC-ACID
  53. Antitumor (Breast) — 1 compounds; BETA-SITOSTEROL
  54. Antitumor (Cervix) — 1 compounds; BETA-SITOSTEROL
  55. Antitumor (Lung) — 1 compounds; BETA-SITOSTEROL
  56. Antiulcer — 1 compounds; HESPERIDIN
  57. Antivaccinia — 1 compounds; HESPERIDIN
  58. Anxiolytic — 1 compounds; HESPERIDIN
  59. Apoptotic — 1 compounds; BETA-SITOSTEROL
  60. Artemicide — 1 compounds; BETA-SITOSTEROL
  61. Atherogenic — 1 compounds; SUCROSE
  62. Bacteristat — 1 compounds; MALIC-ACID
  63. Bruchiphobe — 1 compounds; MALIC-ACID
  64. Calcium-Antagonist — 1 compounds; HESPERIDIN
  65. Cancer-Preventive — 1 compounds; BETA-SITOSTEROL
  66. Candidicide — 1 compounds; BETA-SITOSTEROL
  67. Capillariprotective — 1 compounds; HESPERIDIN
  68. Caspase-8-Inducer — 1 compounds; BETA-SITOSTEROL
  69. Catabolic — 1 compounds; HESPERIDIN
  70. Choleretic — 1 compounds; HESPERIDIN
  71. CNS-Depressant — 1 compounds; HESPERIDIN
  72. Collyrium — 1 compounds; SUCROSE
  73. Cyclooxygenase-Inhibitor — 1 compounds; HESPERIDIN
  74. Cytotoxic — 1 compounds; toxic activity; MEZEREIN
  75. Demulcent — 1 compounds; SUCROSE
  76. Estrogenic — 1 compounds; BETA-SITOSTEROL
  77. Febrifuge — 1 compounds; BETA-SITOSTEROL
  78. Flatugenic — 1 compounds; SUCROSE
  79. Gonadotrophic — 1 compounds; BETA-SITOSTEROL
  80. Hemopoietic — 1 compounds; MALIC-ACID
  81. Hepatoprotective — 1 compounds; toxic activity; BETA-SITOSTEROL
  82. Hypercholesterolemic — 1 compounds; SUCROSE
  83. Hypocholesterolemic — 1 compounds; BETA-SITOSTEROL
  84. Hypoglycemic — 1 compounds; BETA-SITOSTEROL
  85. Laxative? — 1 compounds; MALIC-ACID
  86. Lipoxygenase-Inhibitor — 1 compounds; HESPERIDIN
  87. Mycobactericide — 1 compounds; MALIC-ACID
  88. Preservative — 1 compounds; SUCROSE
  89. ProHLDL — 1 compounds; HESPERIDIN
  90. Sialogogue — 1 compounds; MALIC-ACID
  91. Spermicide — 1 compounds; BETA-SITOSTEROL
  92. Sweetener — 1 compounds; SUCROSE
  93. Toxic — 1 compounds; toxic activity; DAPHNETOXIN
  94. Triglycerigenic — 1 compounds; SUCROSE
  95. Ubiquiot — 1 compounds; BETA-SITOSTEROL
  96. Ulcerogenic — 1 compounds; BETA-SITOSTEROL
  97. Uricogenic — 1 compounds; SUCROSE
  98. Vasopressor — 1 compounds; HESPERIDIN
  99. Vulnerary — 1 compounds; SUCROSE

Toxic compounds

  • BETA-SITOSTEROL — Antimutagenic; Plant; 250 ug/ml
  • BETA-SITOSTEROL — Hepatoprotective; Plant
  • DAPHNETOXIN — Toxic; Bark; LD50=0.25 orl unk
  • DAPHNETOXIN — Toxic; Seed; LD50=0.25 orl unk
  • DAPHNORETIN — Anticarcinomic; Bark; IC97=3 mg/kg
  • HESPERIDIN — Antiallergenic; Plant
  • MEZEREIN — Cytotoxic; Fruit