Datura innoxia (Thorn Apple)

Traditional uses

India

  • Ache(Ear)
  • Anesthetic
  • Demulcent
  • Expectorant
  • Motion-Sickness
  • Ophthalmia
  • Parkinsonianism
  • Phthisis
  • Piles
  • Seasickness
  • Sedative
  • Sore
  • Spasm
  • Tumor

Nepal

  • Asthma
  • Sedative

Pakistan

  • Tumor

Chemicals

Flower

  • ALKALOIDS — 5170
  • HYOSCYAMINE — 1880
  • SCOPOLAMINE — 670

Root

  • ALKALOIDS — 3900
  • CUSCOHYGRINE — 195 to 1170
  • DITIGLOYLTELOIDINE — 80 to 1015
  • HYOSCYAMINE — 860 to 1870
  • METELOIDINE — 40 to 390
  • SCOPOLAMINE — 935 to 2340

Seed

  • ALKALOIDS — 2300 to 4400
  • FAT — 120000 to 220000
  • HYOSCYAMINE — 480 to 925
  • SCOPOLAMINE — 200 to 205
  • PROTEIN — 200000

Shoot

  • ALKALOIDS — 6010
  • HYOSCYAMINE — 1840
  • SCOPOLAMINE — 1660

Plant

  • APOATROPINE
  • ATROPINE
  • 7-HYDROXY-3,6-DITIGLOYLOXYTROPANE
  • PSEUDOTROPINE
  • SCOPOLETIN
  • TIGLOIDINE
  • TROPINE
  • DATURADIOL
  • DATURANOLONE
  • NORHYOSCYAMINE
  • (-)-3ALPHA,6BETA-DITIGLOYLOXYTROPANE

Leaf

  • DITIGLOYLTELOIDINE — 75 to 1650
  • HYOSCYAMINE — 1410 to 3100
  • METELOIDINE — 690 to 1515
  • ALKALOIDS — 2500 to 5500
  • SCOPOLAMINE — 675 to 3850

Fruit

  • ALKALOIDS — 1200 to 7700

Stem

  • ALKALOIDS — 3000
  • DITIGLOYLTELOIDINE — 60 to 600

Tissue Culture

  • BETULINIC-ACID

Activities

  1. Antispasmodic — 6 compounds; APOATROPINE, ATROPINE, HYOSCYAMINE, SCOPOLAMINE, SCOPOLETIN, TIGLOIDINE
  2. Anticholinergic — 5 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE, SCOPOLETIN, TIGLOIDINE
  3. CNS-Depressant — 5 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE, SCOPOLETIN, TIGLOIDINE
  4. Analgesic — 4 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE, SCOPOLETIN
  5. Antimuscarinic — 4 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE, TIGLOIDINE
  6. Antiparkinsonian — 4 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE, TIGLOIDINE
  7. Antiviral — 4 compounds; ATROPINE, BETULINIC-ACID, HYOSCYAMINE, SCOPOLAMINE
  8. Anesthetic — 3 compounds; ATROPINE, SCOPOLAMINE, SCOPOLETIN
  9. Antiasthmatic — 3 compounds; ATROPINE, SCOPOLAMINE, SCOPOLETIN
  10. Antidote (Anticholinesterase) — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  11. Antiemetic — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  12. Antiherpetic — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  13. Antiinflammatory — 3 compounds; BETULINIC-ACID, SCOPOLAMINE, SCOPOLETIN
  14. Antipolio — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  15. Antisialogogue — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  16. Antiulcer — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  17. Antivertigo — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  18. Bronchodilator — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  19. CNS-Stimulant — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLETIN
  20. Mydriatic — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  21. Myorelaxant — 3 compounds; ATROPINE, SCOPOLETIN, TIGLOIDINE
  22. Pesticide — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLETIN
  23. Sedative — 3 compounds; HYOSCYAMINE, SCOPOLAMINE, TIGLOIDINE
  24. Allergenic — 2 compounds; toxic activity; ATROPINE, SCOPOLAMINE
  25. Antianoxic — 2 compounds; ATROPINE, SCOPOLAMINE
  26. Antiarrhythmic — 2 compounds; ATROPINE, SCOPOLETIN
  27. Antibacterial — 2 compounds; BETULINIC-ACID, SCOPOLETIN
  28. Antidote (Tetrodotoxin) — 2 compounds; ATROPINE, SCOPOLAMINE
  29. Antiedemic — 2 compounds; BETULINIC-ACID, SCOPOLETIN
  30. Antimeasles — 2 compounds; HYOSCYAMINE, SCOPOLAMINE
  31. Antitumor — 2 compounds; BETULINIC-ACID, SCOPOLETIN
  32. Apoptotic — 2 compounds; BETULINIC-ACID, SCOPOLETIN
  33. Bronchorelaxant — 2 compounds; HYOSCYAMINE, SCOPOLETIN
  34. Choleretic — 2 compounds; ATROPINE, SCOPOLETIN
  35. Cytotoxic — 2 compounds; toxic activity; BETULINIC-ACID, SCOPOLETIN
  36. Photophobigenic — 2 compounds; HYOSCYAMINE, SCOPOLAMINE
  37. Psychoactive — 2 compounds; HYOSCYAMINE, SCOPOLAMINE
  38. Tachycardic — 2 compounds; ATROPINE, SCOPOLAMINE
  39. Toxic — 2 compounds; toxic activity; HYOSCYAMINE, TROPINE
  40. Aldose-Reductase-Inhibitor — 1 compounds; SCOPOLETIN
  41. Allelochemic — 1 compounds; SCOPOLETIN
  42. Amnesigenic — 1 compounds; SCOPOLAMINE
  43. Anhydrotic — 1 compounds; ATROPINE
  44. Anthelmintic — 1 compounds; BETULINIC-ACID
  45. Antiadrenergic — 1 compounds; SCOPOLETIN
  46. Antiaflatoxin — 1 compounds; SCOPOLETIN
  47. Antibradycardic — 1 compounds; ATROPINE
  48. Antibronchoconstrictor — 1 compounds; SCOPOLETIN
  49. Anticancer — 1 compounds; BETULINIC-ACID
  50. Anticarcinomic — 1 compounds; toxic activity; BETULINIC-ACID
  51. Anticonvulsant — 1 compounds; toxic activity; SCOPOLAMINE
  52. Antideliriant — 1 compounds; SCOPOLAMINE
  53. Antidote (Black Widow) — 1 compounds; ATROPINE
  54. Antidote (Lobelia) — 1 compounds; ATROPINE
  55. Antidote (Muscarine) — 1 compounds; ATROPINE
  56. Antidote (Mushroom) — 1 compounds; ATROPINE
  57. Antidote (Organophosphorus) — 1 compounds; ATROPINE
  58. Antidote (Poison Gas) — 1 compounds; toxic activity; ATROPINE
  59. Antiemphysemic — 1 compounds; ATROPINE
  60. Antienuretic — 1 compounds; ATROPINE
  61. Antifeedant — 1 compounds; SCOPOLETIN
  62. Antihepatotoxic — 1 compounds; toxic activity; SCOPOLETIN
  63. Antihiccup — 1 compounds; SCOPOLAMINE
  64. AntiHIV — 1 compounds; BETULINIC-ACID
  65. Antiiritic — 1 compounds; ATROPINE
  66. Antileukemic — 1 compounds; BETULINIC-ACID
  67. Antileukotrienogenic — 1 compounds; SCOPOLETIN
  68. Antimalarial — 1 compounds; BETULINIC-ACID
  69. Antimanic — 1 compounds; SCOPOLAMINE
  70. Antimelanomic — 1 compounds; BETULINIC-ACID
  71. AntiMeniere's — 1 compounds; SCOPOLAMINE
  72. Antimutagenic — 1 compounds; toxic activity; SCOPOLETIN
  73. Antineuralgic — 1 compounds; HYOSCYAMINE
  74. Antinociceptive — 1 compounds; BETULINIC-ACID
  75. Antioxidant — 1 compounds; SCOPOLETIN
  76. Antiperistaltic — 1 compounds; ATROPINE
  77. Antiperspirant — 1 compounds; ATROPINE
  78. Antipertussic — 1 compounds; ATROPINE
  79. Antiplasmodial — 1 compounds; BETULINIC-ACID
  80. Antiproliferant — 1 compounds; SCOPOLETIN
  81. Antiprostaglandin — 1 compounds; SCOPOLETIN
  82. Antiseptic — 1 compounds; SCOPOLETIN
  83. Antispermatorrheic — 1 compounds; SCOPOLAMINE
  84. Antiuveitic — 1 compounds; ATROPINE
  85. Antivinous — 1 compounds; HYOSCYAMINE
  86. Cancer-Preventive — 1 compounds; SCOPOLETIN
  87. Cardiodepressant — 1 compounds; toxic activity; SCOPOLAMINE
  88. Cardiotonic — 1 compounds; toxic activity; HYOSCYAMINE
  89. Cholagogue — 1 compounds; SCOPOLETIN
  90. Cyclopegic — 1 compounds; SCOPOLAMINE
  91. Dermatitigenic — 1 compounds; toxic activity; SCOPOLAMINE
  92. Fungicide — 1 compounds; SCOPOLETIN
  93. Hepatoprotective — 1 compounds; toxic activity; SCOPOLETIN
  94. Herbicide — 1 compounds; SCOPOLETIN
  95. Hyperkinetic — 1 compounds; SCOPOLAMINE
  96. Hyperpyrexic — 1 compounds; ATROPINE
  97. Hypnotic — 1 compounds; SCOPOLAMINE
  98. Hypoglycemic — 1 compounds; SCOPOLETIN
  99. Hypotensive — 1 compounds; SCOPOLETIN
  100. Insecticide — 1 compounds; ATROPINE
  101. MAO-Inhibitor — 1 compounds; SCOPOLETIN
  102. Musculotropic — 1 compounds; SCOPOLETIN
  103. Neurotoxic — 1 compounds; toxic activity; ATROPINE
  104. Paralytic — 1 compounds; toxic activity; ATROPINE
  105. Phospholipase-A2-Inhibitor — 1 compounds; BETULINIC-ACID
  106. Phytoalexin — 1 compounds; SCOPOLETIN
  107. Phytohormonal — 1 compounds; SCOPOLETIN
  108. Preanesthetic — 1 compounds; SCOPOLAMINE
  109. Prostaglandin-Synthesis-Inhibitor — 1 compounds; BETULINIC-ACID
  110. Psychotomimetic — 1 compounds; ATROPINE
  111. Respiradepressant — 1 compounds; APOATROPINE
  112. Transdermal — 1 compounds; ATROPINE
  113. Tumorigenic — 1 compounds; ATROPINE
  114. Uterosedative — 1 compounds; SCOPOLETIN
  115. Vasodilator — 1 compounds; ATROPINE

Toxic compounds

  • ATROPINE — Allergenic; Plant
  • ATROPINE — Antidote (Poison Gas); Plant
  • ATROPINE — Neurotoxic; Plant
  • ATROPINE — Paralytic; Plant
  • BETULINIC-ACID — Anticarcinomic; Tissue Culture
  • BETULINIC-ACID — Cytotoxic; Tissue Culture; 50-100 ppm
  • HYOSCYAMINE — Cardiotonic; Flower
  • HYOSCYAMINE — Cardiotonic; Leaf
  • HYOSCYAMINE — Cardiotonic; Root
  • HYOSCYAMINE — Cardiotonic; Seed
  • HYOSCYAMINE — Cardiotonic; Shoot
  • HYOSCYAMINE — Toxic; Flower
  • HYOSCYAMINE — Toxic; Leaf
  • HYOSCYAMINE — Toxic; Root
  • HYOSCYAMINE — Toxic; Seed
  • HYOSCYAMINE — Toxic; Shoot
  • SCOPOLAMINE — Allergenic; Flower
  • SCOPOLAMINE — Allergenic; Leaf
  • SCOPOLAMINE — Allergenic; Root
  • SCOPOLAMINE — Allergenic; Seed
  • SCOPOLAMINE — Allergenic; Shoot
  • SCOPOLAMINE — Anticonvulsant; Flower; 5 mg/kg ipr mus
  • SCOPOLAMINE — Anticonvulsant; Leaf; 5 mg/kg ipr mus
  • SCOPOLAMINE — Anticonvulsant; Root; 5 mg/kg ipr mus
  • SCOPOLAMINE — Anticonvulsant; Seed; 5 mg/kg ipr mus
  • SCOPOLAMINE — Anticonvulsant; Shoot; 5 mg/kg ipr mus
  • SCOPOLAMINE — Cardiodepressant; Flower
  • SCOPOLAMINE — Cardiodepressant; Leaf
  • SCOPOLAMINE — Cardiodepressant; Root
  • SCOPOLAMINE — Cardiodepressant; Seed
  • SCOPOLAMINE — Cardiodepressant; Shoot
  • SCOPOLAMINE — Dermatitigenic; Flower
  • SCOPOLAMINE — Dermatitigenic; Leaf
  • SCOPOLAMINE — Dermatitigenic; Root
  • SCOPOLAMINE — Dermatitigenic; Seed
  • SCOPOLAMINE — Dermatitigenic; Shoot
  • SCOPOLETIN — Antihepatotoxic; Plant
  • SCOPOLETIN — Antimutagenic; Plant
  • SCOPOLETIN — Cytotoxic; Plant
  • SCOPOLETIN — Hepatoprotective; Plant
  • TROPINE — Toxic; Plant