Drimys winteri (Winter's Bark)

Traditional uses

Venezuela

• Apertif
• Stimulant

Turkey

• Astringent
• Carminative
• Scurvy
• Stimulant
• Stomachic
• Tonic

Elsewhere

• Balsamic
• Scurvy
• Tonic

Brazil

• Cancer
• Dysentery
• Gastric

Mexico

• Dysentery
• Scurvy
• Tonic
• Ache(Tooth)
• Gastritis

Chile

• Cancer

Chemicals

Leaf

• L-3-BETA-ACETOXYDRIMENIN
• DIHYDROQUERCETIN
• DRIMOL
• KAEMPFEROL
• QUERCETIN

Wood

• CELLULOSE — 353000 to 366000
• LIGNIN — 277000 to 279000
• HEMICELLULOSE — 353000 to 366000

Bark

• CINEOLE
• DRIMINE
• EO — 10000
• FUEGINE
• FURTONOLIDE
• MANNITOL
• VALDIVIOLIDE
• WINTERIN
• CONFERTIFOLIN
• EUGENOL
• L-PINENE
• CARYOPHYLLENE

Plant

• CRYPTOMERIDOL
• ISOTADEONAL
• RHAMNOSE
• TANNIC-ACID
• DRIMENOL
• TADEONOL

Activities

1. Antioxidant — 7 compounds; DIHYDROQUERCETIN, EUGENOL, KAEMPFEROL, LIGNIN, MANNITOL, QUERCETIN, TANNIC-ACID
2. Pesticide — 7 compounds; CARYOPHYLLENE, EUGENOL, KAEMPFEROL, LIGNIN, MANNITOL, QUERCETIN, TANNIC-ACID
3. Antibacterial — 6 compounds; CARYOPHYLLENE, EUGENOL, KAEMPFEROL, LIGNIN, QUERCETIN, TANNIC-ACID
4. Antimutagenic — 6 compounds; toxic activity; DIHYDROQUERCETIN, EUGENOL, KAEMPFEROL, MANNITOL, QUERCETIN, TANNIC-ACID
5. Antispasmodic — 6 compounds; CARYOPHYLLENE, CRYPTOMERIDOL, EUGENOL, KAEMPFEROL, MANNITOL, QUERCETIN
6. Allergenic — 5 compounds; toxic activity; CARYOPHYLLENE, EUGENOL, MANNITOL, QUERCETIN, TANNIC-ACID
7. Antiinflammatory — 5 compounds; CARYOPHYLLENE, EUGENOL, KAEMPFEROL, MANNITOL, QUERCETIN
8. Antitumor — 5 compounds; CARYOPHYLLENE, EUGENOL, KAEMPFEROL, LIGNIN, QUERCETIN
9. Antiulcer — 5 compounds; CARYOPHYLLENE, EUGENOL, KAEMPFEROL, QUERCETIN, TANNIC-ACID
10. Antiviral — 5 compounds; EUGENOL, KAEMPFEROL, LIGNIN, QUERCETIN, TANNIC-ACID
11. Aldose-Reductase-Inhibitor — 4 compounds; CARYOPHYLLENE, KAEMPFEROL, QUERCETIN, TANNIC-ACID
12. Analgesic — 4 compounds; CARYOPHYLLENE, EUGENOL, MANNITOL, QUERCETIN
13. Antifeedant — 4 compounds; CARYOPHYLLENE, EUGENOL, QUERCETIN, TANNIC-ACID
14. Antiherpetic — 4 compounds; EUGENOL, KAEMPFEROL, QUERCETIN, TANNIC-ACID
15. Antiradicular — 4 compounds; EUGENOL, KAEMPFEROL, MANNITOL, QUERCETIN
16. Cytotoxic — 4 compounds; toxic activity; EUGENOL, KAEMPFEROL, QUERCETIN, TANNIC-ACID
17. Fungicide — 4 compounds; CARYOPHYLLENE, EUGENOL, KAEMPFEROL, QUERCETIN
18. Antiaggregant — 3 compounds; EUGENOL, KAEMPFEROL, QUERCETIN
19. Anticariogenic — 3 compounds; CARYOPHYLLENE, QUERCETIN, TANNIC-ACID
20. AntiHIV — 3 compounds; LIGNIN, QUERCETIN, TANNIC-ACID
21. Antinitrosaminic — 3 compounds; LIGNIN, QUERCETIN, TANNIC-ACID
22. Antiseptic — 3 compounds; EUGENOL, KAEMPFEROL, TANNIC-ACID
23. Antistaphylococcic — 3 compounds; CARYOPHYLLENE, EUGENOL, KAEMPFEROL
24. Cancer-Preventive — 3 compounds; EUGENOL, KAEMPFEROL, QUERCETIN
25. Candidicide — 3 compounds; CARYOPHYLLENE, EUGENOL, QUERCETIN
26. COX-2-Inhibitor — 3 compounds; EUGENOL, KAEMPFEROL, QUERCETIN
27. FLavor — 3 compounds; CARYOPHYLLENE, EUGENOL, TANNIC-ACID
28. Hemostat — 3 compounds; CELLULOSE, QUERCETIN, TANNIC-ACID
29. Hepatoprotective — 3 compounds; toxic activity; EUGENOL, KAEMPFEROL, QUERCETIN
30. Vasodilator — 3 compounds; EUGENOL, KAEMPFEROL, QUERCETIN
31. 11B-HSD-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
32. 5-Lipoxygenase-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
33. Antiaflatoxin — 2 compounds; KAEMPFEROL, QUERCETIN
34. Antiallergic — 2 compounds; KAEMPFEROL, QUERCETIN
35. Antiasthmatic — 2 compounds; CARYOPHYLLENE, QUERCETIN
36. Anticancer — 2 compounds; KAEMPFEROL, LIGNIN
37. Anticolitic — 2 compounds; QUERCETIN, TANNIC-ACID
38. Antidermatitic — 2 compounds; toxic activity; CARYOPHYLLENE, QUERCETIN
39. Antidiarrheic — 2 compounds; LIGNIN, TANNIC-ACID
40. Antiedemic — 2 compounds; CARYOPHYLLENE, EUGENOL
41. Antiencephalitic — 2 compounds; QUERCETIN, TANNIC-ACID
42. Antiestrogenic — 2 compounds; EUGENOL, QUERCETIN
43. Antigingivitic — 2 compounds; KAEMPFEROL, TANNIC-ACID
44. Antihistaminic — 2 compounds; KAEMPFEROL, QUERCETIN
45. Antileishmanic — 2 compounds; CARYOPHYLLENE, QUERCETIN
46. Antileukemic — 2 compounds; KAEMPFEROL, QUERCETIN
47. Antipharyngitic — 2 compounds; QUERCETIN, TANNIC-ACID
48. Antiplaque — 2 compounds; KAEMPFEROL, QUERCETIN
49. Antipolio — 2 compounds; QUERCETIN, TANNIC-ACID
50. Antiproliferant — 2 compounds; CARYOPHYLLENE, QUERCETIN
51. Antistreptococcic — 2 compounds; CARYOPHYLLENE, QUERCETIN
52. Antithiamin — 2 compounds; DIHYDROQUERCETIN, QUERCETIN
53. Antitumor-Promoter — 2 compounds; KAEMPFEROL, QUERCETIN
54. Apoptotic — 2 compounds; KAEMPFEROL, QUERCETIN
55. cAMP-Phosphodiesterase-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
56. Carcinogenic — 2 compounds; toxic activity; KAEMPFEROL, QUERCETIN
57. Choleretic — 2 compounds; EUGENOL, KAEMPFEROL
58. Copper-Chelator — 2 compounds; KAEMPFEROL, QUERCETIN
59. Cyclooxygenase-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
60. Diaphoretic? — 2 compounds; KAEMPFEROL, QUERCETIN
61. Diuretic — 2 compounds; KAEMPFEROL, MANNITOL
62. Emetic — 2 compounds; MANNITOL, TANNIC-ACID
63. Estrogenic — 2 compounds; KAEMPFEROL, QUERCETIN
64. HIV-RT-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
65. iNOS-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
66. Inotropic — 2 compounds; KAEMPFEROL, QUERCETIN
67. Insectifuge — 2 compounds; CARYOPHYLLENE, EUGENOL
68. Irritant — 2 compounds; toxic activity; CARYOPHYLLENE, EUGENOL
69. Juvabional — 2 compounds; EUGENOL, QUERCETIN
70. Larvicide — 2 compounds; CARYOPHYLLENE, EUGENOL
71. Laxative — 2 compounds; LIGNIN, MANNITOL
72. Lipoxygenase-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
73. Mutagenic — 2 compounds; toxic activity; KAEMPFEROL, QUERCETIN
74. Neuroprotective — 2 compounds; toxic activity; KAEMPFEROL, QUERCETIN
75. NO-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
76. Perfumery — 2 compounds; CARYOPHYLLENE, EUGENOL
77. Prostaglandin-Synthesis-Inhibitor — 2 compounds; EUGENOL, QUERCETIN
78. Quinone-Reductase-Inducer — 2 compounds; KAEMPFEROL, QUERCETIN
79. Sedative — 2 compounds; CARYOPHYLLENE, EUGENOL
80. Teratologic — 2 compounds; toxic activity; KAEMPFEROL, QUERCETIN
81. TNF-alpha-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
82. Topoisomerase-I-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
83. Topoisomerase-II-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
84. Tyrosinase-Inhibitor — 2 compounds; KAEMPFEROL, QUERCETIN
85. Acaricide — 1 compounds; EUGENOL
86. Aldehyde-Oxidase-Inhibitor — 1 compounds; QUERCETIN
87. Allelochemic — 1 compounds; QUERCETIN
88. Anesthetic — 1 compounds; EUGENOL
89. Anthelmintic — 1 compounds; MANNITOL
90. Antiacne — 1 compounds; CARYOPHYLLENE
91. Antiaging — 1 compounds; QUERCETIN
92. Antialzheimeran — 1 compounds; QUERCETIN
93. Antianacarditic — 1 compounds; TANNIC-ACID
94. Antianaphylactic — 1 compounds; QUERCETIN
95. Antiangiogenic — 1 compounds; QUERCETIN
96. Antiarachidonate — 1 compounds; EUGENOL
97. Antiarthritic — 1 compounds; QUERCETIN
98. Antiatherosclerotic — 1 compounds; QUERCETIN
99. Anticarcinomic (Breast) — 1 compounds; toxic activity; QUERCETIN
100. Anticataract — 1 compounds; QUERCETIN
101. Anticomplementary — 1 compounds; QUERCETIN
102. Anticonvulsant — 1 compounds; toxic activity; EUGENOL
103. Anticoronary — 1 compounds; LIGNIN
104. AntiCrohn's — 1 compounds; QUERCETIN
105. Anticystitic — 1 compounds; QUERCETIN
106. Antidecubitic — 1 compounds; TANNIC-ACID
107. Antidepressant — 1 compounds; QUERCETIN
108. Antidermatotic — 1 compounds; TANNIC-ACID
109. Antidiabetic — 1 compounds; QUERCETIN
110. Antidote — 1 compounds; TANNIC-ACID
111. Antidysenteric — 1 compounds; TANNIC-ACID
112. Antielastase — 1 compounds; QUERCETIN
113. Antienteritic — 1 compounds; TANNIC-ACID
114. Antiescherichic — 1 compounds; QUERCETIN
115. Antifertility — 1 compounds; KAEMPFEROL
116. Antifibrosarcomic — 1 compounds; QUERCETIN
117. Antiflu — 1 compounds; QUERCETIN
118. Antigargantitic — 1 compounds; TANNIC-ACID
119. Antigastric — 1 compounds; QUERCETIN
120. Antigenotoxic — 1 compounds; toxic activity; EUGENOL
121. Antiglaucomic — 1 compounds; MANNITOL
122. Antigonadotropic — 1 compounds; QUERCETIN
123. AntiGTF — 1 compounds; QUERCETIN
124. Antihemorrhoidal — 1 compounds; TANNIC-ACID
125. Antihepatotoxic — 1 compounds; toxic activity; QUERCETIN
126. Antihydrophobic — 1 compounds; QUERCETIN
127. Antihypertensive — 1 compounds; QUERCETIN
128. Antiimplantation — 1 compounds; KAEMPFEROL
129. Antikeratotic — 1 compounds; EUGENOL
130. Antileukotriene — 1 compounds; QUERCETIN
131. Antilipoperoxidant — 1 compounds; QUERCETIN
132. Antilithic — 1 compounds; CRYPTOMERIDOL
133. Antilymphocytic — 1 compounds; KAEMPFEROL
134. Antimalarial — 1 compounds; QUERCETIN
135. Antimelanomic — 1 compounds; QUERCETIN
136. Antimetastatic — 1 compounds; QUERCETIN
137. Antimitotic — 1 compounds; EUGENOL
138. Antimyocarditic — 1 compounds; QUERCETIN
139. Antinephritic — 1 compounds; MANNITOL
140. Antinitrosating — 1 compounds; EUGENOL
141. Antinociceptive — 1 compounds; QUERCETIN
142. Antiobesity — 1 compounds; TANNIC-ACID
143. Antionychyotic — 1 compounds; CARYOPHYLLENE
144. Antiophidic — 1 compounds; TANNIC-ACID
145. Antipancreatitic — 1 compounds; QUERCETIN
146. Antiperiodontal — 1 compounds; QUERCETIN
147. Antiperiodontic — 1 compounds; KAEMPFEROL
148. Antiperistaltic — 1 compounds; QUERCETIN
149. Antipermeability — 1 compounds; QUERCETIN
150. Antiperoxidant — 1 compounds; QUERCETIN
151. Antiplasmodial — 1 compounds; QUERCETIN
152. AntiPMS — 1 compounds; QUERCETIN
153. Antipodriac — 1 compounds; QUERCETIN
154. Antiprostaglandin — 1 compounds; EUGENOL
155. Antiprostanoid — 1 compounds; QUERCETIN
156. Antiprostatitic — 1 compounds; QUERCETIN
157. Antipsoriac — 1 compounds; QUERCETIN
158. Antipyretic — 1 compounds; EUGENOL
159. AntiReye's — 1 compounds; MANNITOL
160. Antirhinitic — 1 compounds; TANNIC-ACID
161. Antisalmonella — 1 compounds; EUGENOL
162. Antiserotonin — 1 compounds; KAEMPFEROL
163. Antistomatitic — 1 compounds; TANNIC-ACID
164. Antithrombic — 1 compounds; QUERCETIN
165. Antithromboxane — 1 compounds; EUGENOL
166. AntiTNF — 1 compounds; EUGENOL
167. Antitonsilitic — 1 compounds; TANNIC-ACID
168. Antitrypanosomic — 1 compounds; QUERCETIN
169. Antitumor (Bladder) — 1 compounds; QUERCETIN
170. Antitumor (Breast) — 1 compounds; QUERCETIN
171. Antitumor (Colon) — 1 compounds; QUERCETIN
172. Antitumor (Lung) — 1 compounds; QUERCETIN
173. Antitumor (Ovary) — 1 compounds; QUERCETIN
174. Antitumor (Skin) — 1 compounds; QUERCETIN
175. Apifuge — 1 compounds; EUGENOL
176. Aromatase-Inhibitor — 1 compounds; KAEMPFEROL
177. Astringent — 1 compounds; TANNIC-ACID
178. ATPase-Inhibitor — 1 compounds; QUERCETIN
179. Bacteristat — 1 compounds; QUERCETIN
180. Bradycardiac — 1 compounds; QUERCETIN
181. Calcium-Antagonist — 1 compounds; EUGENOL
182. Calmodulin-Antagonist — 1 compounds; QUERCETIN
183. Capillariprotective — 1 compounds; QUERCETIN
184. Carcinogenic? — 1 compounds; toxic activity; EUGENOL
185. Carminative — 1 compounds; EUGENOL
186. Catabolic — 1 compounds; QUERCETIN
187. Chelator — 1 compounds; LIGNIN
188. CNS-Depressant — 1 compounds; EUGENOL
189. COMT-Inhibitor — 1 compounds; QUERCETIN
190. Coronary-Dilator — 1 compounds; CRYPTOMERIDOL
191. COX-1-Inhibitor — 1 compounds; EUGENOL
192. Cytochrome-P450-1A2-Inhibitor — 1 compounds; QUERCETIN
193. Cytochrome-P450-Inhibitor — 1 compounds; EUGENOL
194. Deiodinase-Inhibitor — 1 compounds; QUERCETIN
195. Dermatitigenic — 1 compounds; toxic activity; EUGENOL
196. Detoxicant — 1 compounds; toxic activity; TANNIC-ACID
197. Differentiator — 1 compounds; QUERCETIN
198. Enterorelaxant — 1 compounds; EUGENOL
199. Flatugenic — 1 compounds; MANNITOL
200. Gastroprotective — 1 compounds; CARYOPHYLLENE
201. Glucosyl-Transferase-Inhibitor — 1 compounds; QUERCETIN
202. Hepatomagenic — 1 compounds; toxic activity; QUERCETIN
203. Hepatotoxic — 1 compounds; toxic activity; TANNIC-ACID
204. Herbicide — 1 compounds; EUGENOL
205. Hypocholesterolemic — 1 compounds; LIGNIN
206. Hypoglycemic — 1 compounds; QUERCETIN
207. Hypotensive — 1 compounds; KAEMPFEROL
208. ICAM-1-Inhibitor — 1 compounds; KAEMPFEROL
209. Immunostimulant — 1 compounds; TANNIC-ACID
210. Insecticide — 1 compounds; EUGENOL
211. Insulinogenic — 1 compounds; QUERCETIN
212. Iodothyronine-Deiodinase-Inhibitor — 1 compounds; KAEMPFEROL
213. JNK-Inhibitor — 1 compounds; KAEMPFEROL
214. Larvistat — 1 compounds; QUERCETIN
215. MAO-A-Inhibitor — 1 compounds; QUERCETIN
216. MAO-Inhibitor — 1 compounds; KAEMPFEROL
217. Mast-Cell-Stabilizer — 1 compounds; QUERCETIN
218. Metal-Chelator (Copper) — 1 compounds; QUERCETIN
219. Metalloproteinase-Inhibitor — 1 compounds; QUERCETIN
220. MMP-9-Inhibitor — 1 compounds; QUERCETIN
221. Mosquitocide — 1 compounds; CARYOPHYLLENE
222. Motor-Depressant — 1 compounds; EUGENOL
223. NADH-Oxidase-Inhibitor — 1 compounds; QUERCETIN
224. Natriuretic — 1 compounds; KAEMPFEROL
225. Nematicide — 1 compounds; EUGENOL
226. NEP-Inhibitor — 1 compounds; QUERCETIN
227. Nephrotoxic — 1 compounds; toxic activity; MANNITOL
228. Neurotoxic — 1 compounds; toxic activity; EUGENOL
229. NF-kB-Inhibitor — 1 compounds; QUERCETIN
230. NO-Synthase-Inhibitor — 1 compounds; QUERCETIN
231. Ornithine-Decarboxylase-Inhibitor — 1 compounds; QUERCETIN
232. P450-Inducer — 1 compounds; QUERCETIN
233. P450-Inhibitor — 1 compounds; QUERCETIN
234. PAF-Inhibitor — 1 compounds; KAEMPFEROL
235. PGE2-Inhibitor — 1 compounds; QUERCETIN
236. Phospholipase-Inhibitor — 1 compounds; QUERCETIN
237. Plasmodicide — 1 compounds; QUERCETIN
238. Proliferant — 1 compounds; QUERCETIN
239. Protein-Kinase-C-Inhibitor — 1 compounds; QUERCETIN
240. Protisticide — 1 compounds; KAEMPFEROL
241. PTK-Inhibitor — 1 compounds; QUERCETIN
242. Sweetener — 1 compounds; MANNITOL
243. Termiticide — 1 compounds; EUGENOL
244. Termitifuge — 1 compounds; CARYOPHYLLENE
245. Trichomonicide — 1 compounds; EUGENOL
246. Trichomonistat — 1 compounds; EUGENOL
247. Trypsin-Enhancer — 1 compounds; EUGENOL
248. Tumorigenic — 1 compounds; QUERCETIN
249. Tyrosine-Kinase-Inhibitor — 1 compounds; QUERCETIN
250. Ulcerogenic — 1 compounds; EUGENOL
251. Uterotrophic — 1 compounds; KAEMPFEROL
252. Varroacide — 1 compounds; EUGENOL
253. VEGF-Inhibitor — 1 compounds; QUERCETIN
254. Vermifuge — 1 compounds; EUGENOL
255. Xanthine-Oxidase-Inhibitor — 1 compounds; QUERCETIN

Toxic compounds

• CARYOPHYLLENE — Allergenic; Bark
• CARYOPHYLLENE — Antidermatitic; Bark
• CARYOPHYLLENE — Irritant; Bark
• DIHYDROQUERCETIN — Antimutagenic; Leaf; ID50=50-100 nM
• EUGENOL — Allergenic; Bark
• EUGENOL — Anticonvulsant; Bark
• EUGENOL — Antigenotoxic; Bark; 50-500 mg/kg orl mus
• EUGENOL — Antimutagenic; Bark
• EUGENOL — Carcinogenic?; Bark
• EUGENOL — Cytotoxic; Bark; 25 ug/ml
• EUGENOL — Dermatitigenic; Bark
• EUGENOL — Hepatoprotective; Bark; 100 ppm
• EUGENOL — Irritant; Bark
• EUGENOL — Neurotoxic; Bark
• KAEMPFEROL — Antimutagenic; Leaf; ID50=10-40 nM
• KAEMPFEROL — Carcinogenic; Leaf
• KAEMPFEROL — Cytotoxic; Leaf
• KAEMPFEROL — Hepatoprotective; Leaf; IC50=5.46 uM
• KAEMPFEROL — Mutagenic; Leaf
• KAEMPFEROL — Neuroprotective; Leaf
• KAEMPFEROL — Teratologic; Leaf
• MANNITOL — Allergenic; Bark
• MANNITOL — Antimutagenic; Bark
• MANNITOL — Nephrotoxic; Bark
• QUERCETIN — Allergenic; Leaf
• QUERCETIN — Anticarcinomic (Breast); Leaf; IC50=1.5 uM
• QUERCETIN — Antidermatitic; Leaf
• QUERCETIN — Antihepatotoxic; Leaf
• QUERCETIN — Antimutagenic; Leaf; ID50=2-5 nM
• QUERCETIN — Carcinogenic; Leaf; 40,000 ppm (diet) mus
• QUERCETIN — Cytotoxic; Leaf; ED50=70 ug/ml
• QUERCETIN — Hepatomagenic; Leaf; 5,000 ppm (diet) rat
• QUERCETIN — Hepatoprotective; Leaf
• QUERCETIN — Mutagenic; Leaf
• QUERCETIN — Neuroprotective; Leaf; 5-25 uM
• QUERCETIN — Teratologic; Leaf
• TANNIC-ACID — Allergenic; Plant
• TANNIC-ACID — Antimutagenic; Plant
• TANNIC-ACID — Cytotoxic; Plant; 15 ug
• TANNIC-ACID — Detoxicant; Plant
• TANNIC-ACID — Hepatotoxic; Plant