Helleborus niger (Black Hellebore)

Traditional uses

Europe

  • Cancer

Turkey

  • Cardiac
  • Diuretic
  • Emmenagogue
  • Hydragogue
  • Poison
  • Narcotic
  • Cathartic
  • Nervine

Spain

  • Cardiotonic
  • Mydriatic

Elsewhere

  • Emmenagogue
  • Cardiostimulant

Tradition unspecified

  • Poison

UK

  • Rodenticide

Chemicals

Rhizome

  • DESGLUCOHELLEBRIN
  • HELLEBORIN
  • HELLEBRIGENIN
  • L-RHAMNOSE
  • SPIROST-5,15(27)-DIEN-1BETA,3BETA,11ALPHA-TRIOL
  • ACONITIC-ACID
  • GLUCOSE
  • HELLEBRIN

Seed

  • FAT — 352000
  • PROTEIN — 212000

Flower

  • KAEMPFEROL-3,7-DIGLUCOSIDE
  • KAEMPFEROL-3-SAMBUBIOSIDE
  • KAEMPFEROL-3-0-SOPHOROSIDE
  • KAEMPFEROL-3-SAMBUBIOSIDE-7-GLUCOSIDE

Plant

  • STROPHANTHOBIOSE

Activities

  1. Narcotic — 2 compounds; toxic activity; HELLEBORIN, HELLEBRIN
  2. Acetylcholinergic — 1 compounds; GLUCOSE
  3. Anticarcinomic — 1 compounds; toxic activity; HELLEBRIN
  4. Antiedemic — 1 compounds; GLUCOSE
  5. Antihepatotoxic — 1 compounds; toxic activity; GLUCOSE
  6. Antiketotic — 1 compounds; GLUCOSE
  7. Antivaricose — 1 compounds; GLUCOSE
  8. Digitalic — 1 compounds; HELLEBRIN
  9. Hyperglycemic — 1 compounds; GLUCOSE
  10. Memory-Enhancer — 1 compounds; GLUCOSE
  11. Perfumery — 1 compounds; ACONITIC-ACID

Toxic compounds

  • GLUCOSE — Antihepatotoxic; Rhizome
  • HELLEBORIN — Narcotic; Rhizome
  • HELLEBRIN — Anticarcinomic; Rhizome; ED50=17 ppb
  • HELLEBRIN — Narcotic; Rhizome