Hura crepitans (Sandbox Tree)

Traditional uses

Guiana

  • Anodyne

Elsewhere

  • Antidote
  • Aperient
  • Dentifuge
  • Insecticide
  • Leprosy
  • Piscicide
  • Poison(Arrow)
  • Repellant(Insect)
  • Rheumatism
  • Skin
  • Arrow
  • Vermifuge
  • Poison

Latin America

  • Carcinogenic
  • Poison

Dominican Republic

  • Emetic
  • Poison
  • Purgative

India

  • Poison
  • Purgative

Java

  • Purgative
  • Sore

Venezuela

  • Purgative

Haiti

  • Rheumatism
  • Piscicide
  • Anodyne

Brazil

  • Leprosy
  • Elephantiasis

Mexico

  • Poison
  • Purgative

Chemicals

Latex Exudate

  • BUTYROSPERMOL
  • HURAIN
  • HURINE
  • 24-METHYLENE-CYCLOARTENOL
  • CYCLOARTENOL
  • HURATOXIN
  • INOSITOL

Leaf

  • P-COUMARIC-ACID
  • FERULIC-ACID
  • KAEMPFEROL

Seed

  • CREPITIN

Activities

  1. Pesticide — 5 compounds; CYCLOARTENOL, FERULIC-ACID, HURATOXIN, KAEMPFEROL, P-COUMARIC-ACID
  2. Antibacterial — 4 compounds; CYCLOARTENOL, FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  3. Antiinflammatory — 3 compounds; CYCLOARTENOL, FERULIC-ACID, KAEMPFEROL
  4. Antileukemic — 3 compounds; FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  5. Antioxidant — 3 compounds; FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  6. Antispasmodic — 3 compounds; FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  7. Antitumor — 3 compounds; FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  8. Cancer-Preventive — 3 compounds; FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  9. Choleretic — 3 compounds; FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  10. Fungicide — 3 compounds; FERULIC-ACID, KAEMPFEROL, P-COUMARIC-ACID
  11. Aldose-Reductase-Inhibitor — 2 compounds; KAEMPFEROL, P-COUMARIC-ACID
  12. Allelopathic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
  13. Antiaggregant — 2 compounds; FERULIC-ACID, KAEMPFEROL
  14. Antiallergic — 2 compounds; FERULIC-ACID, KAEMPFEROL
  15. Antifertility — 2 compounds; KAEMPFEROL, P-COUMARIC-ACID
  16. Antihepatotoxic — 2 compounds; toxic activity; FERULIC-ACID, P-COUMARIC-ACID
  17. Antiherpetic — 2 compounds; FERULIC-ACID, KAEMPFEROL
  18. Antimutagenic — 2 compounds; toxic activity; FERULIC-ACID, KAEMPFEROL
  19. Antinitrosaminic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
  20. Antiradicular — 2 compounds; FERULIC-ACID, KAEMPFEROL
  21. Antiseptic — 2 compounds; KAEMPFEROL, P-COUMARIC-ACID
  22. Antiserotonin — 2 compounds; FERULIC-ACID, KAEMPFEROL
  23. Antistaphylococcic — 2 compounds; CYCLOARTENOL, KAEMPFEROL
  24. Antitumor-Promoter — 2 compounds; FERULIC-ACID, KAEMPFEROL
  25. Antiviral — 2 compounds; FERULIC-ACID, KAEMPFEROL
  26. Cytotoxic — 2 compounds; toxic activity; KAEMPFEROL, P-COUMARIC-ACID
  27. Diaphoretic? — 2 compounds; KAEMPFEROL, P-COUMARIC-ACID
  28. Hepatoprotective — 2 compounds; toxic activity; FERULIC-ACID, KAEMPFEROL
  29. Lipoxygenase-Inhibitor — 2 compounds; KAEMPFEROL, P-COUMARIC-ACID
  30. Prostaglandigenic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
  31. Prostaglandin-Synthesis-Inhibitor — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
  32. Tyrosinase-Inhibitor — 2 compounds; KAEMPFEROL, P-COUMARIC-ACID
  33. Ubiquiot — 2 compounds; CYCLOARTENOL, INOSITOL
  34. 11B-HSD-Inhibitor — 1 compounds; KAEMPFEROL
  35. 5-Lipoxygenase-Inhibitor — 1 compounds; KAEMPFEROL
  36. Analgesic — 1 compounds; FERULIC-ACID
  37. Antiaflatoxin — 1 compounds; KAEMPFEROL
  38. Antialopecic — 1 compounds; INOSITOL
  39. Antiarrhythmic — 1 compounds; FERULIC-ACID
  40. Anticancer — 1 compounds; KAEMPFEROL
  41. Anticancer (Colon) — 1 compounds; FERULIC-ACID
  42. Anticancer (Forestomach) — 1 compounds; FERULIC-ACID
  43. Anticancer (Liver) — 1 compounds; FERULIC-ACID
  44. Anticancer (Skin) — 1 compounds; FERULIC-ACID
  45. Anticarcinogenic — 1 compounds; toxic activity; FERULIC-ACID
  46. Anticirrhotic — 1 compounds; INOSITOL
  47. Anticlastogen — 1 compounds; P-COUMARIC-ACID
  48. Antidiabetic? — 1 compounds; INOSITOL
  49. Antidysmenorrheic — 1 compounds; FERULIC-ACID
  50. Antiestrogenic — 1 compounds; FERULIC-ACID
  51. Antigingivitic — 1 compounds; KAEMPFEROL
  52. Antihistaminic — 1 compounds; KAEMPFEROL
  53. Antiimplantation — 1 compounds; KAEMPFEROL
  54. Antilymphocytic — 1 compounds; KAEMPFEROL
  55. Antimitotic — 1 compounds; FERULIC-ACID
  56. Antineoplastic — 1 compounds; FERULIC-ACID
  57. Antineuropathic? — 1 compounds; toxic activity; INOSITOL
  58. Antiperiodontic — 1 compounds; KAEMPFEROL
  59. Antiperoxidant — 1 compounds; P-COUMARIC-ACID
  60. Antiplaque — 1 compounds; KAEMPFEROL
  61. Antirheumatic — 1 compounds; CYCLOARTENOL
  62. Antithrombic — 1 compounds; FERULIC-ACID
  63. Antitumor (Colon) — 1 compounds; FERULIC-ACID
  64. Antitumor (Forestomach) — 1 compounds; FERULIC-ACID
  65. Antitumor (Liver) — 1 compounds; FERULIC-ACID
  66. Antitumor (Skin) — 1 compounds; FERULIC-ACID
  67. Antiulcer — 1 compounds; KAEMPFEROL
  68. Apoptotic — 1 compounds; KAEMPFEROL
  69. Aromatase-Inhibitor — 1 compounds; KAEMPFEROL
  70. Arteriodilator — 1 compounds; FERULIC-ACID
  71. cAMP-Phosphodiesterase-Inhibitor — 1 compounds; KAEMPFEROL
  72. Candidicide — 1 compounds; FERULIC-ACID
  73. Carcinogenic — 1 compounds; toxic activity; KAEMPFEROL
  74. Cardiac — 1 compounds; FERULIC-ACID
  75. Chemopreventive — 1 compounds; P-COUMARIC-ACID
  76. Cholagogue — 1 compounds; FERULIC-ACID
  77. Cholesterolytic — 1 compounds; INOSITOL
  78. Co-carcinogenic — 1 compounds; toxic activity; HURATOXIN
  79. Copper-Chelator — 1 compounds; KAEMPFEROL
  80. COX-2-Inhibitor — 1 compounds; KAEMPFEROL
  81. Cyclooxygenase-Inhibitor — 1 compounds; KAEMPFEROL
  82. Diuretic — 1 compounds; KAEMPFEROL
  83. Estrogenic — 1 compounds; KAEMPFEROL
  84. Hepatotropic — 1 compounds; toxic activity; FERULIC-ACID
  85. Herbicide — 1 compounds; FERULIC-ACID
  86. HIV-RT-Inhibitor — 1 compounds; KAEMPFEROL
  87. Hydrocholerectic — 1 compounds; FERULIC-ACID
  88. Hypocholesterolemic — 1 compounds; CYCLOARTENOL
  89. Hypolipidemic — 1 compounds; FERULIC-ACID
  90. Hypotensive — 1 compounds; KAEMPFEROL
  91. ICAM-1-Inhibitor — 1 compounds; KAEMPFEROL
  92. Immunostimulant — 1 compounds; FERULIC-ACID
  93. iNOS-Inhibitor — 1 compounds; KAEMPFEROL
  94. Inotropic — 1 compounds; KAEMPFEROL
  95. Insectifuge — 1 compounds; FERULIC-ACID
  96. Iodothyronine-Deiodinase-Inhibitor — 1 compounds; KAEMPFEROL
  97. JNK-Inhibitor — 1 compounds; KAEMPFEROL
  98. Lipotropic — 1 compounds; INOSITOL
  99. MAO-Inhibitor — 1 compounds; KAEMPFEROL
  100. Metal-Chelator — 1 compounds; FERULIC-ACID
  101. Mutagenic — 1 compounds; toxic activity; KAEMPFEROL
  102. Natriuretic — 1 compounds; KAEMPFEROL
  103. Neuroprotective — 1 compounds; toxic activity; KAEMPFEROL
  104. NO-Inhibitor — 1 compounds; KAEMPFEROL
  105. Ornithine-Decarboxylase-Inhibitor — 1 compounds; FERULIC-ACID
  106. PAF-Inhibitor — 1 compounds; KAEMPFEROL
  107. Phagocytotic — 1 compounds; FERULIC-ACID
  108. Piscicide — 1 compounds; HURATOXIN
  109. Preservative — 1 compounds; FERULIC-ACID
  110. Protisticide — 1 compounds; KAEMPFEROL
  111. Quinone-Reductase-Inducer — 1 compounds; KAEMPFEROL
  112. Sunscreen — 1 compounds; FERULIC-ACID
  113. Sweetener — 1 compounds; INOSITOL
  114. Teratologic — 1 compounds; toxic activity; KAEMPFEROL
  115. TNF-alpha-Inhibitor — 1 compounds; KAEMPFEROL
  116. Topoisomerase-I-Inhibitor — 1 compounds; KAEMPFEROL
  117. Topoisomerase-II-Inhibitor — 1 compounds; KAEMPFEROL
  118. Uterosedative — 1 compounds; FERULIC-ACID
  119. Uterotrophic — 1 compounds; KAEMPFEROL
  120. Vasodilator — 1 compounds; KAEMPFEROL

Toxic compounds

  • FERULIC-ACID — Anticarcinogenic; Leaf
  • FERULIC-ACID — Antihepatotoxic; Leaf
  • FERULIC-ACID — Antimutagenic; Leaf
  • FERULIC-ACID — Hepatoprotective; Leaf
  • FERULIC-ACID — Hepatotropic; Leaf
  • HURATOXIN — Co-carcinogenic; Latex Exudate
  • INOSITOL — Antineuropathic?; Latex Exudate; 2 g/day
  • KAEMPFEROL — Antimutagenic; Leaf; ID50=10-40 nM
  • KAEMPFEROL — Carcinogenic; Leaf
  • KAEMPFEROL — Cytotoxic; Leaf
  • KAEMPFEROL — Hepatoprotective; Leaf; IC50=5.46 uM
  • KAEMPFEROL — Mutagenic; Leaf
  • KAEMPFEROL — Neuroprotective; Leaf
  • KAEMPFEROL — Teratologic; Leaf
  • P-COUMARIC-ACID — Antihepatotoxic; Leaf
  • P-COUMARIC-ACID — Cytotoxic; Leaf