Jatropha gossypifolia (Spanish Physic Nut)

Traditional uses

Curacao

  • Ache(Stomach)
  • Cold
  • Disinfectant
  • Gargle
  • Laxative
  • Sore(Throat)
  • Wound
  • Cough
  • Sore
  • Venereal
  • Asthma
  • Diabetes
  • Diarrhea
  • Gall
  • Hematochezia
  • Poison

Elsewhere

  • Ache(Stomach)
  • Depurative
  • Emetic
  • Emmenagogue
  • Itch
  • Purgative
  • Sore
  • Tongue
  • Venereal
  • Eczema
  • Mammary
  • Carbuncle

Venezuela

  • Bilious
  • Dyspepsia
  • Emetic
  • Leprosy
  • Purgative
  • Stomachic
  • Bite(Snake)
  • Venereal
  • Diarrhea

Costa Rica

  • Cancer

Java

  • Candlenut
  • Purgative

Panama

  • Depurative
  • Vermifuge
  • Laxative
  • Tumor

Trinidad

  • Depurative
  • Diarrhea
  • Dyspepsia
  • Emetic
  • Piles
  • Purgative
  • Rash
  • Rectitis
  • Sore
  • Venereal
  • Witchcraft

Haiti

  • Dropsy
  • Eczema
  • Emetic
  • Hydropsy
  • Purgative

West Indies

  • Emmenagogue
  • Febrifuge
  • Fever
  • Swelling(Mammary)

Sumatra

  • Leprosy

India(Munda)

  • Urogenital

Dominican Republic

  • Sore

India

  • Antibiotic

Latin America

  • Poison

Chemicals

Leaf

  • APIGENIN
  • HISTAMINE
  • VITEXIN
  • ISOVITEXIN
  • TANNIN

Seed

  • CURCIN
  • 2-PIPEONYLIDENE-2-VERYTRYL-3-R-GAMMA-BUTYROLACTONE

Bark

  • ISOPHYTOSTEROL — 3500
  • JATROPHINE — 4000

Plant

  • JATROPHOLONES
  • BETA-SITOSTEROL
  • GADAIN

Root

  • JATROPHONE

Activities

  1. Antioxidant — 5 compounds; APIGENIN, BETA-SITOSTEROL, ISOVITEXIN, TANNIN, VITEXIN
  2. Cancer-Preventive — 5 compounds; APIGENIN, BETA-SITOSTEROL, ISOVITEXIN, TANNIN, VITEXIN
  3. Antitumor — 4 compounds; APIGENIN, JATROPHOLONES, JATROPHONE, TANNIN
  4. Antibacterial — 3 compounds; APIGENIN, BETA-SITOSTEROL, TANNIN
  5. Antiinflammatory — 3 compounds; APIGENIN, BETA-SITOSTEROL, VITEXIN
  6. Antimutagenic — 3 compounds; toxic activity; APIGENIN, BETA-SITOSTEROL, TANNIN
  7. Antiviral — 3 compounds; APIGENIN, BETA-SITOSTEROL, TANNIN
  8. Hypotensive — 3 compounds; APIGENIN, HISTAMINE, VITEXIN
  9. Pesticide — 3 compounds; APIGENIN, BETA-SITOSTEROL, TANNIN
  10. ACE-Inhibitor — 2 compounds; ISOVITEXIN, VITEXIN
  11. Antiarrhythmic — 2 compounds; APIGENIN, VITEXIN
  12. Anticancer (Lung) — 2 compounds; APIGENIN, BETA-SITOSTEROL
  13. Antidermatitic — 2 compounds; toxic activity; APIGENIN, VITEXIN
  14. Antiestrogenic — 2 compounds; APIGENIN, BETA-SITOSTEROL
  15. Antihistaminic — 2 compounds; APIGENIN, VITEXIN
  16. AntiHIV — 2 compounds; APIGENIN, TANNIN
  17. Antileukemic — 2 compounds; APIGENIN, BETA-SITOSTEROL
  18. Antiophidic — 2 compounds; BETA-SITOSTEROL, TANNIN
  19. Antithyroid — 2 compounds; APIGENIN, VITEXIN
  20. Antitumor (Breast) — 2 compounds; APIGENIN, BETA-SITOSTEROL
  21. Antitumor (Lung) — 2 compounds; APIGENIN, BETA-SITOSTEROL
  22. Apoptotic — 2 compounds; APIGENIN, BETA-SITOSTEROL
  23. Cyclooxygenase-Inhibitor — 2 compounds; APIGENIN, TANNIN
  24. Cytotoxic — 2 compounds; toxic activity; APIGENIN, JATROPHONE
  25. Estrogenic — 2 compounds; APIGENIN, BETA-SITOSTEROL
  26. Hepatoprotective — 2 compounds; toxic activity; BETA-SITOSTEROL, TANNIN
  27. MAO-Inhibitor — 2 compounds; APIGENIN, TANNIN
  28. Ornithine-Decarboxylase-Inhibitor — 2 compounds; APIGENIN, TANNIN
  29. Radioprotective — 2 compounds; APIGENIN, HISTAMINE
  30. Ulcerogenic — 2 compounds; BETA-SITOSTEROL, HISTAMINE
  31. Vasodilator — 2 compounds; APIGENIN, HISTAMINE
  32. Xanthine-Oxidase-Inhibitor — 2 compounds; APIGENIN, TANNIN
  33. 11B-HSD-Inhibitor — 1 compounds; APIGENIN
  34. Aldose-Reductase-Inhibitor — 1 compounds; VITEXIN
  35. Allergenic — 1 compounds; toxic activity; HISTAMINE
  36. Androgenic — 1 compounds; BETA-SITOSTEROL
  37. Angiogenic — 1 compounds; BETA-SITOSTEROL
  38. Anorexic — 1 compounds; BETA-SITOSTEROL
  39. Anthelmintic — 1 compounds; TANNIN
  40. AntiADD — 1 compounds; APIGENIN
  41. Antiadenomic — 1 compounds; BETA-SITOSTEROL
  42. Antiaflatoxin — 1 compounds; APIGENIN
  43. Antiaggregant — 1 compounds; APIGENIN
  44. Antiaging — 1 compounds; APIGENIN
  45. Antiallergic — 1 compounds; APIGENIN
  46. Antiandrogenic — 1 compounds; BETA-SITOSTEROL
  47. Antiangiogenic — 1 compounds; APIGENIN
  48. Antibradiquinic — 1 compounds; VITEXIN
  49. Anticancer — 1 compounds; TANNIN
  50. Anticancer (Breast) — 1 compounds; BETA-SITOSTEROL
  51. Anticancer (Cervix) — 1 compounds; BETA-SITOSTEROL
  52. Anticariogenic — 1 compounds; TANNIN
  53. Antichilblain — 1 compounds; HISTAMINE
  54. Anticomplementary — 1 compounds; APIGENIN
  55. Antidiarrheic — 1 compounds; TANNIN
  56. Antidysenteric — 1 compounds; TANNIN
  57. Antiedemic — 1 compounds; BETA-SITOSTEROL
  58. Antifeedant — 1 compounds; BETA-SITOSTEROL
  59. Antifertility — 1 compounds; BETA-SITOSTEROL
  60. Antigonadotrophic — 1 compounds; BETA-SITOSTEROL
  61. Antihepatotoxic — 1 compounds; toxic activity; TANNIN
  62. Antiherpetic — 1 compounds; APIGENIN
  63. Antihyperlipoproteinaemic — 1 compounds; BETA-SITOSTEROL
  64. Antihypertensive — 1 compounds; TANNIN
  65. Antilipolytic — 1 compounds; TANNIN
  66. Antilymphomic — 1 compounds; BETA-SITOSTEROL
  67. Antimelanomic — 1 compounds; APIGENIN
  68. AntiMeniere's — 1 compounds; HISTAMINE
  69. Antimetastatic — 1 compounds; APIGENIN
  70. Antimigraine — 1 compounds; HISTAMINE
  71. Antinephritic — 1 compounds; TANNIN
  72. Antiperistaltic — 1 compounds; APIGENIN
  73. Antiprogestational — 1 compounds; BETA-SITOSTEROL
  74. Antiproliferant — 1 compounds; APIGENIN
  75. Antiprostaglandin — 1 compounds; BETA-SITOSTEROL
  76. Antiprostatadenomic — 1 compounds; BETA-SITOSTEROL
  77. Antiprostatitic — 1 compounds; BETA-SITOSTEROL
  78. Antipyretic — 1 compounds; BETA-SITOSTEROL
  79. Antiradicular — 1 compounds; TANNIN
  80. Antirenitic — 1 compounds; TANNIN
  81. Antiserotoninic — 1 compounds; VITEXIN
  82. Antispasmodic — 1 compounds; APIGENIN
  83. Antistress — 1 compounds; APIGENIN
  84. Antitumor (Cervix) — 1 compounds; BETA-SITOSTEROL
  85. Antitumor (Skin) — 1 compounds; APIGENIN
  86. Antitumor-Promoter — 1 compounds; TANNIN
  87. Antiulcer — 1 compounds; TANNIN
  88. Anxiolytic — 1 compounds; APIGENIN
  89. Aphidifuge — 1 compounds; VITEXIN
  90. Aromatase-Inhibitor — 1 compounds; APIGENIN
  91. Artemicide — 1 compounds; BETA-SITOSTEROL
  92. Beta-Glucuronidase-Inhibitor — 1 compounds; APIGENIN
  93. Bronchoconstrictor — 1 compounds; HISTAMINE
  94. Bronchostimulant — 1 compounds; HISTAMINE
  95. Calcium-Antagonist? — 1 compounds; APIGENIN
  96. cAMP-Phosphodiesterase-Inhibitor — 1 compounds; VITEXIN
  97. Candidicide — 1 compounds; BETA-SITOSTEROL
  98. Carcinogenic — 1 compounds; toxic activity; TANNIN
  99. Cardiovascular — 1 compounds; toxic activity; HISTAMINE
  100. Caspase-8-Inducer — 1 compounds; BETA-SITOSTEROL
  101. Chelator — 1 compounds; TANNIN
  102. Choleretic — 1 compounds; APIGENIN
  103. CNS-Depressant — 1 compounds; APIGENIN
  104. COX-1-Inhibitor — 1 compounds; APIGENIN
  105. COX-2-Inhibitor — 1 compounds; APIGENIN
  106. Cytochrome-P450-1A1-Inhibitor — 1 compounds; APIGENIN
  107. Deiodinase-Inhibitor — 1 compounds; APIGENIN
  108. Differentiator — 1 compounds; APIGENIN
  109. Diuretic — 1 compounds; APIGENIN
  110. DNA-Protective — 1 compounds; APIGENIN
  111. Febrifuge — 1 compounds; BETA-SITOSTEROL
  112. Gastrostimulant — 1 compounds; HISTAMINE
  113. Glucosyl-Transferase-Inhibitor — 1 compounds; TANNIN
  114. Goitrogenic — 1 compounds; VITEXIN
  115. Gonadotrophic — 1 compounds; BETA-SITOSTEROL
  116. HIF-1alpha-Inhibitor — 1 compounds; APIGENIN
  117. Histaminic — 1 compounds; HISTAMINE
  118. Hyaluronidase-Inhibitor — 1 compounds; APIGENIN
  119. Hypocholesterolemic — 1 compounds; BETA-SITOSTEROL
  120. Hypoglycemic — 1 compounds; BETA-SITOSTEROL
  121. Hypolipidemic — 1 compounds; BETA-SITOSTEROL
  122. ICAM-1-Inhibitor — 1 compounds; APIGENIN
  123. IKK-Inhibitor — 1 compounds; APIGENIN
  124. Immunosuppressant — 1 compounds; TANNIN
  125. iNOS-Inhibitor — 1 compounds; APIGENIN
  126. Inotropic — 1 compounds; APIGENIN
  127. Interleukin-6-Inhibitor — 1 compounds; APIGENIN
  128. Irritant — 1 compounds; toxic activity; HISTAMINE
  129. Lipoxygenase-Inhibitor — 1 compounds; TANNIN
  130. MAPK-Inhibitor — 1 compounds; APIGENIN
  131. Musculotropic — 1 compounds; APIGENIN
  132. Mutagenic — 1 compounds; toxic activity; APIGENIN
  133. Myorelaxant — 1 compounds; APIGENIN
  134. Myostimulant — 1 compounds; HISTAMINE
  135. NADH-Oxidase-Inhibitor — 1 compounds; APIGENIN
  136. NF-kB-Inhibitor — 1 compounds; APIGENIN
  137. NO-Synthase-Inhibitor — 1 compounds; APIGENIN
  138. Nodulation-Signal — 1 compounds; APIGENIN
  139. P21-Inducer — 1 compounds; APIGENIN
  140. PKC-Inhibitor — 1 compounds; APIGENIN
  141. Polyamine-Synthesis-Inhibitor — 1 compounds; APIGENIN
  142. Progestational — 1 compounds; APIGENIN
  143. Protein-Kinase-C-Inhibitor — 1 compounds; APIGENIN
  144. Psychotropic — 1 compounds; TANNIN
  145. PTK-Inhibitor — 1 compounds; APIGENIN
  146. Quinone-Reductase-Inducer — 1 compounds; APIGENIN
  147. Secretogogue — 1 compounds; HISTAMINE
  148. Sedative — 1 compounds; APIGENIN
  149. Spasmogenic — 1 compounds; HISTAMINE
  150. Spermicide — 1 compounds; BETA-SITOSTEROL
  151. Sunscreen — 1 compounds; APIGENIN
  152. Tachycardic — 1 compounds; HISTAMINE
  153. Thyroid-Peroxidase-Inhibitor — 1 compounds; VITEXIN
  154. TNF-alpha-Inhibitor — 1 compounds; APIGENIN
  155. Topoisomerase-I-Inhibitor — 1 compounds; APIGENIN
  156. Topoisomerase-II-Inhibitor — 1 compounds; APIGENIN
  157. Ubiquiot — 1 compounds; BETA-SITOSTEROL
  158. Uterotrophic — 1 compounds; APIGENIN
  159. VEGF-Inhibitor — 1 compounds; APIGENIN

Toxic compounds

  • APIGENIN — Antidermatitic; Leaf
  • APIGENIN — Antimutagenic; Leaf; ID50=10-40 nM
  • APIGENIN — Cytotoxic; Leaf; IC88=10 ug/ml
  • APIGENIN — Mutagenic; Leaf
  • BETA-SITOSTEROL — Antimutagenic; Plant; 250 ug/ml
  • BETA-SITOSTEROL — Hepatoprotective; Plant
  • HISTAMINE — Allergenic; Leaf
  • HISTAMINE — Cardiovascular; Leaf; 0.15 mg/kg ivn rbt
  • HISTAMINE — Irritant; Leaf
  • JATROPHONE — Cytotoxic; Root; 0.17
  • TANNIN — Antihepatotoxic; Leaf
  • TANNIN — Antimutagenic; Leaf
  • TANNIN — Carcinogenic; Leaf
  • TANNIN — Hepatoprotective; Leaf
  • VITEXIN — Antidermatitic; Leaf