Mandragora officinarum (Mandrake)

Traditional uses

Elsewhere

  • Anesthetic
  • Hypnotic
  • Mydriatic
  • Sedative

Europe

  • Asthma
  • Cough
  • Poison
  • Tumor
  • Hayfever

India

  • Narcotic

Belgium

  • Tumor

Chemicals

Root

  • ALKALOIDS — 3000 to 4000
  • ATROPINE — 10 to 20
  • CUSCOHYGRINE
  • MANDRAGORINE
  • SCOPINE
  • APOATROPINE
  • HYOSCYAMINE — 2500 to 3500
  • SCOPOLAMINE — 30 to 50
  • 3,6-DITIGLOYLOXYTROPANE
  • BELLADONNINE

Seed

  • FAT — 226000
  • PROTEIN — 221000

Plant

  • NORHYOSCYAMINE
  • SCOPOLETIN
  • SCOPOLINE
  • TROPIC-ACID
  • 3-ALPHA-TIGLOYLOXYTROPANE
  • CHRYSATROPIC-ACID

Activities

  1. Anticholinergic — 5 compounds; ATROPINE, HYOSCYAMINE, MANDRAGORINE, SCOPOLAMINE, SCOPOLETIN
  2. Antispasmodic — 5 compounds; APOATROPINE, ATROPINE, HYOSCYAMINE, SCOPOLAMINE, SCOPOLETIN
  3. Analgesic — 4 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE, SCOPOLETIN
  4. Bronchodilator — 4 compounds; ATROPINE, HYOSCYAMINE, MANDRAGORINE, SCOPOLAMINE
  5. CNS-Depressant — 4 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE, SCOPOLETIN
  6. CNS-Stimulant — 4 compounds; ATROPINE, HYOSCYAMINE, MANDRAGORINE, SCOPOLETIN
  7. Mydriatic — 4 compounds; ATROPINE, HYOSCYAMINE, MANDRAGORINE, SCOPOLAMINE
  8. Anesthetic — 3 compounds; ATROPINE, SCOPOLAMINE, SCOPOLETIN
  9. Antiasthmatic — 3 compounds; ATROPINE, SCOPOLAMINE, SCOPOLETIN
  10. Antidote (Anticholinesterase) — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  11. Antiemetic — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  12. Antiherpetic — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  13. Antimuscarinic — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  14. Antiparkinsonian — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  15. Antipolio — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  16. Antisialogogue — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  17. Antiulcer — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  18. Antivertigo — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  19. Antiviral — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLAMINE
  20. Pesticide — 3 compounds; ATROPINE, HYOSCYAMINE, SCOPOLETIN
  21. Allergenic — 2 compounds; toxic activity; ATROPINE, SCOPOLAMINE
  22. Antianoxic — 2 compounds; ATROPINE, SCOPOLAMINE
  23. Antiarrhythmic — 2 compounds; ATROPINE, SCOPOLETIN
  24. Antidote (Tetrodotoxin) — 2 compounds; ATROPINE, SCOPOLAMINE
  25. Antiinflammatory — 2 compounds; SCOPOLAMINE, SCOPOLETIN
  26. Antimeasles — 2 compounds; HYOSCYAMINE, SCOPOLAMINE
  27. Bronchorelaxant — 2 compounds; HYOSCYAMINE, SCOPOLETIN
  28. Choleretic — 2 compounds; ATROPINE, SCOPOLETIN
  29. Myorelaxant — 2 compounds; ATROPINE, SCOPOLETIN
  30. Photophobigenic — 2 compounds; HYOSCYAMINE, SCOPOLAMINE
  31. Psychoactive — 2 compounds; HYOSCYAMINE, SCOPOLAMINE
  32. Sedative — 2 compounds; HYOSCYAMINE, SCOPOLAMINE
  33. Tachycardic — 2 compounds; ATROPINE, SCOPOLAMINE
  34. Aldose-Reductase-Inhibitor — 1 compounds; SCOPOLETIN
  35. Allelochemic — 1 compounds; SCOPOLETIN
  36. Amnesigenic — 1 compounds; SCOPOLAMINE
  37. Anesthetic-potentiator — 1 compounds; BELLADONNINE
  38. Anhydrotic — 1 compounds; ATROPINE
  39. Antiadrenergic — 1 compounds; SCOPOLETIN
  40. Antiaflatoxin — 1 compounds; SCOPOLETIN
  41. Antibacterial — 1 compounds; SCOPOLETIN
  42. Antibradycardic — 1 compounds; ATROPINE
  43. Antibronchoconstrictor — 1 compounds; SCOPOLETIN
  44. Anticonvulsant — 1 compounds; toxic activity; SCOPOLAMINE
  45. Antideliriant — 1 compounds; SCOPOLAMINE
  46. Antidote (Black Widow) — 1 compounds; ATROPINE
  47. Antidote (Lobelia) — 1 compounds; ATROPINE
  48. Antidote (Muscarine) — 1 compounds; ATROPINE
  49. Antidote (Mushroom) — 1 compounds; ATROPINE
  50. Antidote (Organophosphorus) — 1 compounds; ATROPINE
  51. Antidote (Poison Gas) — 1 compounds; toxic activity; ATROPINE
  52. Antiedemic — 1 compounds; SCOPOLETIN
  53. Antiemphysemic — 1 compounds; ATROPINE
  54. Antienuretic — 1 compounds; ATROPINE
  55. Antifeedant — 1 compounds; SCOPOLETIN
  56. Antihepatotoxic — 1 compounds; toxic activity; SCOPOLETIN
  57. Antihiccup — 1 compounds; SCOPOLAMINE
  58. Antiiritic — 1 compounds; ATROPINE
  59. Antileukotrienogenic — 1 compounds; SCOPOLETIN
  60. Antimanic — 1 compounds; SCOPOLAMINE
  61. AntiMeniere's — 1 compounds; SCOPOLAMINE
  62. Antimutagenic — 1 compounds; toxic activity; SCOPOLETIN
  63. Antineuralgic — 1 compounds; HYOSCYAMINE
  64. Antioxidant — 1 compounds; SCOPOLETIN
  65. Antiperistaltic — 1 compounds; ATROPINE
  66. Antiperspirant — 1 compounds; ATROPINE
  67. Antipertussic — 1 compounds; ATROPINE
  68. Antiproliferant — 1 compounds; SCOPOLETIN
  69. Antiprostaglandin — 1 compounds; SCOPOLETIN
  70. Antiseptic — 1 compounds; SCOPOLETIN
  71. Antispermatorrheic — 1 compounds; SCOPOLAMINE
  72. Antitumor — 1 compounds; SCOPOLETIN
  73. Antiuveitic — 1 compounds; ATROPINE
  74. Antivinous — 1 compounds; HYOSCYAMINE
  75. Apoptotic — 1 compounds; SCOPOLETIN
  76. Cancer-Preventive — 1 compounds; SCOPOLETIN
  77. Cardiodepressant — 1 compounds; toxic activity; SCOPOLAMINE
  78. Cardiotonic — 1 compounds; toxic activity; HYOSCYAMINE
  79. Cholagogue — 1 compounds; SCOPOLETIN
  80. Cyclopegic — 1 compounds; SCOPOLAMINE
  81. Cytotoxic — 1 compounds; toxic activity; SCOPOLETIN
  82. Dermatitigenic — 1 compounds; toxic activity; SCOPOLAMINE
  83. Fungicide — 1 compounds; SCOPOLETIN
  84. Hepatoprotective — 1 compounds; toxic activity; SCOPOLETIN
  85. Herbicide — 1 compounds; SCOPOLETIN
  86. Hyperkinetic — 1 compounds; SCOPOLAMINE
  87. Hyperpyrexic — 1 compounds; ATROPINE
  88. Hypnotic — 1 compounds; SCOPOLAMINE
  89. Hypoglycemic — 1 compounds; SCOPOLETIN
  90. Hypotensive — 1 compounds; SCOPOLETIN
  91. Insecticide — 1 compounds; ATROPINE
  92. MAO-Inhibitor — 1 compounds; SCOPOLETIN
  93. Musculotropic — 1 compounds; SCOPOLETIN
  94. Neurotoxic — 1 compounds; toxic activity; ATROPINE
  95. Paralytic — 1 compounds; toxic activity; ATROPINE
  96. Phytoalexin — 1 compounds; SCOPOLETIN
  97. Phytohormonal — 1 compounds; SCOPOLETIN
  98. Preanesthetic — 1 compounds; SCOPOLAMINE
  99. Psychotomimetic — 1 compounds; ATROPINE
  100. Respiradepressant — 1 compounds; APOATROPINE
  101. Toxic — 1 compounds; toxic activity; HYOSCYAMINE
  102. Transdermal — 1 compounds; ATROPINE
  103. Tumorigenic — 1 compounds; ATROPINE
  104. Uterosedative — 1 compounds; SCOPOLETIN
  105. Vasodilator — 1 compounds; ATROPINE

Toxic compounds

  • ATROPINE — Allergenic; Root
  • ATROPINE — Antidote (Poison Gas); Root
  • ATROPINE — Neurotoxic; Root
  • ATROPINE — Paralytic; Root
  • HYOSCYAMINE — Cardiotonic; Root
  • HYOSCYAMINE — Toxic; Root
  • SCOPOLAMINE — Allergenic; Root
  • SCOPOLAMINE — Anticonvulsant; Root; 5 mg/kg ipr mus
  • SCOPOLAMINE — Cardiodepressant; Root
  • SCOPOLAMINE — Dermatitigenic; Root
  • SCOPOLETIN — Antihepatotoxic; Plant
  • SCOPOLETIN — Antimutagenic; Plant
  • SCOPOLETIN — Cytotoxic; Plant
  • SCOPOLETIN — Hepatoprotective; Plant