Phyllanthus niruri (Seed On The Leaf)

Traditional uses

Haiti

• Ache(Stomach)
• Carminative
• Colic
• Digestive
• Diuretic
• Fever
• Malaria
• Stomachic
• Tenesmus

Malaya

• Sting(Caterpillar)
• Dermatosis
• Diarrhea
• Diuretic
• Piscicide
• Renosis
• Vertigo
• Itch
• Miscarriage
• Syphilis

Java

• Cough
• Gonorrhea
• Ache(Stomach)

Reunion

• Diarrhea
• Dropsy
• Blennorrhagia

Samoa

• Diuretic
• Poultice

Africa

• Dysentery
• Dyspepsia

Marianas I

• Dysentery
• Itch
• Rectitis
• Vaginitis

Philippines

• Emmenagogue
• Fever
• Tonic

Bahamas

• Fever
• Flu
• Laxative
• Ache(Stomach)
• Apertif
• Typhoid

Puerto Rico

• Fever

Gold Coast

• Gonorrhea

India

• Gonorrhea
• Tumor(Abdomen)
• Diuretic
• Dysentery

Brazil

• Kidney
• Fever

Dominican Republic

• Malaria
• Diabetes

Sudan

• Medicine

Chemicals

Plant

• BREVIFOLIN-CARBOXYLIC-ACID
• LINTETRALIN
• 4-METHOXY-SECURININE
• QUERCETIN
• QUERCETIN-HETEROSIDE
• QUERCITRIN
• ASTRAGALIN
• METHYL-SALICYLATE
• NIRURETIN
• PHYLLOCHRYSINE
• RUTIN
• QUERCETOL
• HYPOPHYLLANTHINE
• 4-METHOXY-NORSECURININE
• NIRURIN
• SAPONINS

Root

• LUPA-20(29)-ENE-3-BETA-OL
• LUPA-20(29)-ENE-3-BETA-OL-ACETATE
• 3,5,7-TRIHYDROXYFLAVONAL-4'-O-ALPHA-L-(-)-RHAMNOPYRANOSIDE
• LUPEOL
• 5,3',4'-TRIHYDROXYFLAVONONE-7-O-ALPHA-L-(-)-RHAMNOPYRANOSIDE

Leaf

• NIRANTHIN
• NIRTETRALIN
• CYMENE
• PHYLTETRALIN
• PHYLLANTHIN
• LIMONENE

Activities

1. Antiinflammatory — 6 compounds; LIMONENE, LUPEOL, METHYL-SALICYLATE, QUERCETIN, QUERCITRIN, RUTIN
2. Pesticide — 6 compounds; LIMONENE, LUPEOL, METHYL-SALICYLATE, QUERCETIN, QUERCITRIN, RUTIN
3. Aldose-Reductase-Inhibitor — 5 compounds; ASTRAGALIN, BREVIFOLIN-CARBOXYLIC-ACID, QUERCETIN, QUERCITRIN, RUTIN
4. Antimutagenic — 5 compounds; toxic activity; LIMONENE, QUERCETIN, QUERCITRIN, RUTIN, SAPONINS
5. Antioxidant — 5 compounds; LUPEOL, METHYL-SALICYLATE, QUERCETIN, QUERCITRIN, RUTIN
6. Antitumor — 5 compounds; LIMONENE, LUPEOL, QUERCETIN, QUERCITRIN, RUTIN
7. Antiviral — 5 compounds; LIMONENE, LUPEOL, QUERCETIN, QUERCITRIN, RUTIN
8. Cancer-Preventive — 5 compounds; LIMONENE, METHYL-SALICYLATE, QUERCETIN, QUERCITRIN, RUTIN
9. Antibacterial — 4 compounds; LIMONENE, QUERCETIN, QUERCITRIN, RUTIN
10. Antifeedant — 4 compounds; LIMONENE, QUERCETIN, QUERCITRIN, RUTIN
11. Antiflu — 4 compounds; LIMONENE, LUPEOL, QUERCETIN, QUERCITRIN
12. Antihepatotoxic — 4 compounds; toxic activity; PHYLLANTHIN, QUERCETIN, QUERCITRIN, RUTIN
13. Antispasmodic — 4 compounds; LIMONENE, QUERCETIN, QUERCITRIN, RUTIN
14. Hypotensive — 4 compounds; ASTRAGALIN, LUPEOL, QUERCITRIN, RUTIN
15. Allelochemic — 3 compounds; LIMONENE, QUERCETIN, RUTIN
16. Allergenic — 3 compounds; toxic activity; LIMONENE, METHYL-SALICYLATE, QUERCETIN
17. Anticataract — 3 compounds; QUERCETIN, QUERCITRIN, RUTIN
18. Antiedemic — 3 compounds; LUPEOL, QUERCITRIN, RUTIN
19. Antiherpetic — 3 compounds; QUERCETIN, QUERCITRIN, RUTIN
20. Antimalarial — 3 compounds; LUPEOL, QUERCETIN, RUTIN
21. Antiperoxidant — 3 compounds; LUPEOL, QUERCETIN, RUTIN
22. Antiradicular — 3 compounds; METHYL-SALICYLATE, QUERCETIN, RUTIN
23. Antiulcer — 3 compounds; QUERCETIN, QUERCITRIN, RUTIN
24. Apoptotic — 3 compounds; LIMONENE, QUERCETIN, RUTIN
25. Hemostat — 3 compounds; QUERCETIN, QUERCITRIN, RUTIN
26. Immunomodulator — 3 compounds; LIMONENE, RUTIN, SAPONINS
27. Insectiphile — 3 compounds; METHYL-SALICYLATE, QUERCITRIN, RUTIN
28. ACE-Inhibitor — 2 compounds; ASTRAGALIN, QUERCITRIN
29. Aldehyde-Oxidase-Inhibitor — 2 compounds; QUERCETIN, RUTIN
30. Analgesic — 2 compounds; METHYL-SALICYLATE, QUERCETIN
31. Antiaggregant — 2 compounds; QUERCETIN, RUTIN
32. Antiallergic — 2 compounds; QUERCETIN, RUTIN
33. Antiangiogenic — 2 compounds; LUPEOL, QUERCETIN
34. Antiasthmatic — 2 compounds; LIMONENE, QUERCETIN
35. Antiatherosclerotic — 2 compounds; QUERCETIN, RUTIN
36. Anticancer — 2 compounds; LIMONENE, RUTIN
37. Anticapillary-Fragility — 2 compounds; QUERCETOL, RUTIN
38. Antidermatitic — 2 compounds; toxic activity; QUERCETIN, RUTIN
39. Antidiabetic — 2 compounds; QUERCETIN, RUTIN
40. Antihistaminic — 2 compounds; QUERCETIN, RUTIN
41. Antihypertensive — 2 compounds; QUERCETIN, RUTIN
42. Antileukemic — 2 compounds; ASTRAGALIN, QUERCETIN
43. Antilithic — 2 compounds; LIMONENE, LUPEOL
44. Antimelanomic — 2 compounds; QUERCETIN, RUTIN
45. Antimetastatic — 2 compounds; QUERCETIN, RUTIN
46. Antinociceptive — 2 compounds; QUERCETIN, RUTIN
47. Antiproliferant — 2 compounds; QUERCETIN, RUTIN
48. Antipurpuric — 2 compounds; QUERCITRIN, RUTIN
49. Antiseptic — 2 compounds; LIMONENE, METHYL-SALICYLATE
50. Antithrombogenic — 2 compounds; QUERCITRIN, RUTIN
51. Antitrypanosomic — 2 compounds; QUERCETIN, RUTIN
52. Antitumor (Breast) — 2 compounds; LIMONENE, QUERCETIN
53. Antitumor (Colon) — 2 compounds; LIMONENE, QUERCETIN
54. Antitumor (Lung) — 2 compounds; QUERCETIN, SAPONINS
55. Antitumor (Ovary) — 2 compounds; QUERCETIN, SAPONINS
56. Antitumor-Promoter — 2 compounds; QUERCETIN, RUTIN
57. cAMP-Phosphodiesterase-Inhibitor — 2 compounds; QUERCETIN, RUTIN
58. Capillariprotective — 2 compounds; QUERCETIN, RUTIN
59. Catabolic — 2 compounds; QUERCETIN, RUTIN
60. Chemopreventive — 2 compounds; LIMONENE, RUTIN
61. Cytotoxic — 2 compounds; toxic activity; LUPEOL, QUERCETIN
62. Detoxicant — 2 compounds; toxic activity; LIMONENE, QUERCITRIN
63. Expectorant — 2 compounds; ASTRAGALIN, LIMONENE
64. FLavor — 2 compounds; LIMONENE, METHYL-SALICYLATE
65. Fungicide — 2 compounds; METHYL-SALICYLATE, QUERCETIN
66. Hepatomagenic — 2 compounds; toxic activity; QUERCETIN, RUTIN
67. Hepatoprotective — 2 compounds; toxic activity; QUERCETIN, RUTIN
68. Hypoglycemic — 2 compounds; QUERCETIN, QUERCITRIN
69. Insecticide — 2 compounds; LIMONENE, RUTIN
70. Insectifuge — 2 compounds; LIMONENE, METHYL-SALICYLATE
71. Juvabional — 2 compounds; QUERCETIN, RUTIN
72. Larvistat — 2 compounds; QUERCETIN, RUTIN
73. Lipoxygenase-Inhibitor — 2 compounds; QUERCETIN, RUTIN
74. MAO-A-Inhibitor — 2 compounds; QUERCETIN, QUERCITRIN
75. Mutagenic — 2 compounds; toxic activity; QUERCETIN, RUTIN
76. Myorelaxant — 2 compounds; LIMONENE, RUTIN
77. Ornithine-Decarboxylase-Inhibitor — 2 compounds; LIMONENE, QUERCETIN
78. P450-Inducer — 2 compounds; LIMONENE, QUERCETIN
79. Topoisomerase-II-Inhibitor — 2 compounds; QUERCETIN, RUTIN
80. Vasodilator — 2 compounds; QUERCETIN, RUTIN
81. Vasopressor — 2 compounds; QUERCITRIN, RUTIN
82. 11B-HSD-Inhibitor — 1 compounds; QUERCETIN
83. 5-HT-Inhibitor — 1 compounds; RUTIN
84. 5-Lipoxygenase-Inhibitor — 1 compounds; QUERCETIN
85. Acaricide — 1 compounds; LIMONENE
86. AChE-Inhibitor — 1 compounds; LIMONENE
87. Anaphrodisiac — 1 compounds; METHYL-SALICYLATE
88. Antiacetylcholinesterase — 1 compounds; LIMONENE
89. Antiadenomic — 1 compounds; LIMONENE
90. Antiaflatoxin — 1 compounds; QUERCETIN
91. Antiaging — 1 compounds; QUERCETIN
92. Antialzheimeran — 1 compounds; QUERCETIN
93. Antialzheimeran? — 1 compounds; LIMONENE
94. Antianaphylactic — 1 compounds; QUERCETIN
95. Antiapoplectic — 1 compounds; RUTIN
96. Antiarrhythmic — 1 compounds; QUERCITRIN
97. Antiarthritic — 1 compounds; QUERCETIN
98. Antiatherogenic — 1 compounds; RUTIN
99. Anticarcinomic (Breast) — 1 compounds; toxic activity; QUERCETIN
100. Anticariogenic — 1 compounds; QUERCETIN
101. Anticlastogen — 1 compounds; RUTIN
102. Anticolitic — 1 compounds; QUERCETIN
103. Anticomplementary — 1 compounds; QUERCETIN
104. Anticonvulsant — 1 compounds; toxic activity; RUTIN
105. AntiCrohn's — 1 compounds; QUERCETIN
106. AntiCVI — 1 compounds; RUTIN
107. Anticystitic — 1 compounds; QUERCETIN
108. Antidementia — 1 compounds; RUTIN
109. Antidepressant — 1 compounds; QUERCETIN
110. AntiEBV — 1 compounds; LUPEOL
111. Antielastase — 1 compounds; QUERCETIN
112. Antiencephalitic — 1 compounds; QUERCETIN
113. Antierythemic — 1 compounds; RUTIN
114. Antiescherichic — 1 compounds; QUERCETIN
115. Antiesophagitic — 1 compounds; LIMONENE
116. Antiestrogenic — 1 compounds; QUERCETIN
117. Antifibrosarcomic — 1 compounds; QUERCETIN
118. Antigastric — 1 compounds; QUERCETIN
119. Antiglaucomic — 1 compounds; RUTIN
120. Antigonadotropic — 1 compounds; QUERCETIN
121. AntiGTF — 1 compounds; QUERCETIN
122. Antihematuric — 1 compounds; RUTIN
123. Antihemorrhagic — 1 compounds; QUERCITRIN
124. Antihemorrhoidal — 1 compounds; RUTIN
125. Antihepatomic — 1 compounds; toxic activity; SAPONINS
126. AntiHIV — 1 compounds; QUERCETIN
127. Antihydrophobic — 1 compounds; QUERCETIN
128. Antihyperglycemic — 1 compounds; LUPEOL
129. Antileishmanic — 1 compounds; QUERCETIN
130. Antileukotriene — 1 compounds; QUERCETIN
131. Antilipoperoxidant — 1 compounds; QUERCETIN
132. Antilymphomic — 1 compounds; LIMONENE
133. Antimetastatic (Stomach) — 1 compounds; LIMONENE
134. Antimyocarditic — 1 compounds; QUERCETIN
135. Antinephritic — 1 compounds; RUTIN
136. Antinitrosaminic — 1 compounds; QUERCETIN
137. Antiobesity — 1 compounds; LIMONENE
138. Antioxalate — 1 compounds; LUPEOL
139. Antipancreatitic — 1 compounds; QUERCETIN
140. Antiperiodontal — 1 compounds; QUERCETIN
141. Antiperistaltic — 1 compounds; QUERCETIN
142. Antipermeability — 1 compounds; QUERCETIN
143. Antipharyngitic — 1 compounds; QUERCETIN
144. Antiplaque — 1 compounds; QUERCETIN
145. Antiplasmodial — 1 compounds; QUERCETIN
146. Antiplatelet — 1 compounds; RUTIN
147. AntiPMS — 1 compounds; QUERCETIN
148. Antipodriac — 1 compounds; QUERCETIN
149. Antipolio — 1 compounds; QUERCETIN
150. Antiprostaglandin — 1 compounds; LUPEOL
151. Antiprostanoid — 1 compounds; QUERCETIN
152. Antiprostatitic — 1 compounds; QUERCETIN
153. Antiprotozoal — 1 compounds; RUTIN
154. Antipsoriac — 1 compounds; QUERCETIN
155. Antipyretic — 1 compounds; METHYL-SALICYLATE
156. Antirheumatalgic — 1 compounds; METHYL-SALICYLATE
157. Antirheumatic — 1 compounds; LUPEOL
158. Antistaphylococcic — 1 compounds; QUERCITRIN
159. Antistreptococcic — 1 compounds; QUERCETIN
160. Antisunburn — 1 compounds; RUTIN
161. Antitartar — 1 compounds; METHYL-SALICYLATE
162. Antithiamin — 1 compounds; QUERCETIN
163. Antithrombic — 1 compounds; QUERCETIN
164. Antithyroid — 1 compounds; RUTIN
165. Antitumor (Bladder) — 1 compounds; QUERCETIN
166. Antitumor (Pancreas) — 1 compounds; LIMONENE
167. Antitumor (Prostate) — 1 compounds; LIMONENE
168. Antitumor (Skin) — 1 compounds; QUERCETIN
169. Antitumor (Stomach) — 1 compounds; LIMONENE
170. Antiurethrotic — 1 compounds; LUPEOL
171. Antivaricose — 1 compounds; RUTIN
172. ATPase-Inhibitor — 1 compounds; QUERCETIN
173. Bacteristat — 1 compounds; QUERCETIN
174. Bradycardiac — 1 compounds; QUERCETIN
175. Bronchoprotectant — 1 compounds; LIMONENE
176. Calmodulin-Antagonist — 1 compounds; QUERCETIN
177. Candidicide — 1 compounds; QUERCETIN
178. Candidistat — 1 compounds; LIMONENE
179. Carcinogenic — 1 compounds; toxic activity; QUERCETIN
180. Cardiotonic — 1 compounds; toxic activity; QUERCITRIN
181. Carminative — 1 compounds; METHYL-SALICYLATE
182. Choleretic — 1 compounds; QUERCITRIN
183. Cholesterolytic — 1 compounds; LIMONENE
184. CNS-Depressant — 1 compounds; QUERCITRIN
185. COMT-Inhibitor — 1 compounds; QUERCETIN
186. Copper-Chelator — 1 compounds; QUERCETIN
187. Counterirritant — 1 compounds; toxic activity; METHYL-SALICYLATE
188. COX-2-Inhibitor — 1 compounds; QUERCETIN
189. Cyclooxygenase-Activator — 1 compounds; QUERCITRIN
190. Cyclooxygenase-Inhibitor — 1 compounds; QUERCETIN
191. Cytochrome-P450-1A2-Inhibitor — 1 compounds; QUERCETIN
192. Cytoprotective — 1 compounds; RUTIN
193. Deiodinase-Inhibitor — 1 compounds; QUERCETIN
194. Dentifrice — 1 compounds; METHYL-SALICYLATE
195. Diaphoretic? — 1 compounds; QUERCETIN
196. Differentiator — 1 compounds; QUERCETIN
197. Diuretic — 1 compounds; QUERCITRIN
198. Dye — 1 compounds; QUERCITRIN
199. Enterocontractant — 1 compounds; LIMONENE
200. Estrogenic — 1 compounds; QUERCETIN
201. Estrogenic? — 1 compounds; RUTIN
202. FPTase-Inhibitor — 1 compounds; LUPEOL
203. Fungiphilic — 1 compounds; LIMONENE
204. Fungistat — 1 compounds; LIMONENE
205. Glucosyl-Transferase-Inhibitor — 1 compounds; QUERCETIN
206. GST-Inducer — 1 compounds; LIMONENE
207. Hepatotonic — 1 compounds; toxic activity; QUERCITRIN
208. Herbicide — 1 compounds; LIMONENE
209. Herpetifuge — 1 compounds; METHYL-SALICYLATE
210. Histaminic — 1 compounds; LIMONENE
211. HIV-RT-Inhibitor — 1 compounds; QUERCETIN
212. Hypocholesterolemic — 1 compounds; RUTIN
213. Immunostimulant — 1 compounds; ASTRAGALIN
214. iNOS-Inhibitor — 1 compounds; QUERCETIN
215. Inotropic — 1 compounds; QUERCETIN
216. Insulinogenic — 1 compounds; QUERCETIN
217. Interleukin-6-Inhibitor — 1 compounds; LIMONENE
218. Irritant — 1 compounds; toxic activity; LIMONENE
219. Lipolytic — 1 compounds; LIMONENE
220. MAO-Inhibitor — 1 compounds; QUERCITRIN
221. Mast-Cell-Stabilizer — 1 compounds; QUERCETIN
222. Metal-Chelator (Copper) — 1 compounds; QUERCETIN
223. Metalloproteinase-Inhibitor — 1 compounds; QUERCETIN
224. MMP-9-Inhibitor — 1 compounds; QUERCETIN
225. Myoprotective — 1 compounds; RUTIN
226. NADH-Oxidase-Inhibitor — 1 compounds; QUERCETIN
227. Nematicide — 1 compounds; LIMONENE
228. NEP-Inhibitor — 1 compounds; QUERCETIN
229. Neuroprotective — 1 compounds; toxic activity; QUERCETIN
230. NF-kB-Inhibitor — 1 compounds; QUERCETIN
231. NO-Genic — 1 compounds; LIMONENE
232. NO-Inhibitor — 1 compounds; QUERCETIN
233. NO-Synthase-Inhibitor — 1 compounds; QUERCETIN
234. Oviposition-Stimulant — 1 compounds; RUTIN
235. Ozone-Scavenger — 1 compounds; LIMONENE
236. P450-Inhibitor — 1 compounds; QUERCETIN
237. PAF-Inhibitor — 1 compounds; RUTIN
238. Paralytic — 1 compounds; toxic activity; QUERCITRIN
239. Perfumery — 1 compounds; METHYL-SALICYLATE
240. Peristaltic — 1 compounds; LIMONENE
241. PGE2-Inhibitor — 1 compounds; QUERCETIN
242. Phospholipase-Inhibitor — 1 compounds; QUERCETIN
243. Photosensitizer — 1 compounds; LIMONENE
244. Piscicide — 1 compounds; PHYLLANTHIN
245. Plasmodicide — 1 compounds; QUERCETIN
246. Proliferant — 1 compounds; QUERCETIN
247. Prostaglandin-Synthesis-Inhibitor — 1 compounds; QUERCETIN
248. Protein-Kinase-C-Inhibitor — 1 compounds; QUERCETIN
249. Protisticide — 1 compounds; RUTIN
250. PTK-Inhibitor — 1 compounds; QUERCETIN
251. Quinone-Reductase-Inducer — 1 compounds; QUERCETIN
252. Radioprotective — 1 compounds; RUTIN
253. Sedative — 1 compounds; LIMONENE
254. Sunscreen — 1 compounds; RUTIN
255. Teratologic — 1 compounds; toxic activity; QUERCETIN
256. TNF-alpha-Inhibitor — 1 compounds; QUERCETIN
257. TOPO-2-Inhibitor — 1 compounds; LUPEOL
258. Topoisomerase-I-Inhibitor — 1 compounds; QUERCETIN
259. Transdermal — 1 compounds; LIMONENE
260. Tumorigenic — 1 compounds; QUERCETIN
261. Tyrosinase-Inhibitor — 1 compounds; QUERCETIN
262. Tyrosine-Kinase-Inhibitor — 1 compounds; QUERCETIN
263. VEGF-Inhibitor — 1 compounds; QUERCETIN
264. Xanthine-Oxidase-Inhibitor — 1 compounds; QUERCETIN

Toxic compounds

• LIMONENE — Allergenic; Leaf; 1/20th carene
• LIMONENE — Antimutagenic; Leaf
• LIMONENE — Detoxicant; Leaf
• LIMONENE — Irritant; Leaf
• LUPEOL — Cytotoxic; Root; 50-500 ppm
• METHYL-SALICYLATE — Allergenic; Plant
• METHYL-SALICYLATE — Counterirritant; Plant
• PHYLLANTHIN — Antihepatotoxic; Leaf
• QUERCETIN — Allergenic; Plant
• QUERCETIN — Anticarcinomic (Breast); Plant; IC50=1.5 uM
• QUERCETIN — Antidermatitic; Plant
• QUERCETIN — Antihepatotoxic; Plant
• QUERCETIN — Antimutagenic; Plant; ID50=2-5 nM
• QUERCETIN — Carcinogenic; Plant; 40,000 ppm (diet) mus
• QUERCETIN — Cytotoxic; Plant; ED50=70 ug/ml
• QUERCETIN — Hepatomagenic; Plant; 5,000 ppm (diet) rat
• QUERCETIN — Hepatoprotective; Plant
• QUERCETIN — Mutagenic; Plant
• QUERCETIN — Neuroprotective; Plant; 5-25 uM
• QUERCETIN — Teratologic; Plant
• QUERCITRIN — Antihepatotoxic; Plant
• QUERCITRIN — Antimutagenic; Plant; ID50=2-5 nM
• QUERCITRIN — Cardiotonic; Plant
• QUERCITRIN — Detoxicant; Plant
• QUERCITRIN — Hepatotonic; Plant
• QUERCITRIN — Paralytic; Plant
• RUTIN — Anticonvulsant; Plant
• RUTIN — Antidermatitic; Plant
• RUTIN — Antihepatotoxic; Plant
• RUTIN — Antimutagenic; Plant; ID50=2-5 nM
• RUTIN — Hepatomagenic; Plant; 20,000 ppm (diet) rat
• RUTIN — Hepatoprotective; Plant; 20 mg/kg rat
• RUTIN — Mutagenic; Plant
• SAPONINS — Antihepatomic; Plant
• SAPONINS — Antimutagenic; Plant