Picrorhiza kurrooa (Picrorhiza)

Traditional uses

Malaya (Import)

  • Bilious
  • Dyspepsia

Chemicals

Plant

  • 25-ACETOXY-2BETA-GLUCOSYLOXY-3,16,20-TRIHYDROXY-9-METHYL-18-NORLANOST-5,23-DIEN-22-ONE
  • 2BETA-GLUCOSYLOXY-3,16,20,25-TETRAHYDROXY-9-METHYL-19-NORLANOSTA-5,23-DIENE-11,22-DIONE
  • 2BETA-GLUCOSYLOXY-16,20,22-TRIHYDROXY-9-METHYL-19-NORLANOSTA-5,24-DIENE-3,11-DIONE
  • AMPHICOSIDE
  • ANDROSIN
  • APOCYNINE
  • KUTKOSIDE
  • PICROSIDE-III
  • PROTOCATECHUIC-ACID

Rhizome

  • APOCYNIN
  • GLUCOSIDO-VANILLOYL-GLUCOSE
  • KURRIN — 5000
  • KUTHINOL
  • KUTHIRTEROL
  • KUTKISTEROL — 1800
  • KUTKIN — 30000 to 40000
  • KUTKIOL — 600
  • PICROSIDE-II
  • VANILLIC-ACID — 1000
  • GLUCOSE
  • PICRORHIZIN
  • TRIPALMITIN
  • D-MANNITOL — 5000

Root

  • ARVENIN-III — 35
  • KUTKOSIDE — 2400
  • PICROSIDE-I — 470
  • 2-BETA-GLUCOSYLOXY-CUCURBITACIN-O — 47
  • 6-FERULOYLCATALPOL — 59
  • 6-TRANS-FERULOYLCATALPOL
  • AMPHICOSIDE — 706 to 36000
  • ANDROSIN — 176
  • APOCYNIN
  • CUCURBITACIN-B — 47
  • CUCURBITACIN-GLYCOSIDE
  • CUCURBITACIN-Q-2-O-BETA-D-GLUCOSIDE — 35
  • MINECOSIDE — 59
  • MINECOSIDES
  • PICEIN — 118
  • PICROSIDE
  • VERONICOSIDE — 47
  • 23,24-DIHYDROCUCURBITACIN-B — 24

Juice

  • CATALPOL
  • CINNAMIC-ACID-6-BETA-D-GLUCOSIDE

Activities

  1. Antiinflammatory — 4 compounds; APOCYNIN, CUCURBITACIN-B, PROTOCATECHUIC-ACID, VANILLIC-ACID
  2. Choleretic — 4 compounds; KUTKIN, PICROSIDE-I, PICROSIDE-II, VANILLIC-ACID
  3. Antiasthmatic — 3 compounds; ANDROSIN, APOCYNINE, PROTOCATECHUIC-ACID
  4. Antihepatotoxic — 3 compounds; toxic activity; CUCURBITACIN-B, GLUCOSE, PROTOCATECHUIC-ACID
  5. Antioxidant — 3 compounds; APOCYNIN, PROTOCATECHUIC-ACID, VANILLIC-ACID
  6. Hepatotoxic — 3 compounds; toxic activity; PICROSIDE-I, PICROSIDE-II, PROTOCATECHUIC-ACID
  7. Antibacterial — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  8. Antileukemic — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  9. Antiperoxidant — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  10. Antiradicular — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  11. Antiseptic — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  12. Antitumor — 2 compounds; CUCURBITACIN-B, VANILLIC-ACID
  13. Cancer-Preventive — 2 compounds; CUCURBITACIN-B, VANILLIC-ACID
  14. Diuretic — 2 compounds; CATALPOL, KUTKIN
  15. Fungicide — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  16. Hepatoprotective — 2 compounds; toxic activity; PICROSIDE-I, PICROSIDE-II
  17. Laxative — 2 compounds; KUTKIN, VANILLIC-ACID
  18. Pesticide — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  19. Ubiquiot — 2 compounds; PROTOCATECHUIC-ACID, VANILLIC-ACID
  20. Acetylcholinergic — 1 compounds; GLUCOSE
  21. Aldose-Reductase-Inhibitor — 1 compounds; VANILLIC-ACID
  22. Allelopathic — 1 compounds; VANILLIC-ACID
  23. Allergenic — 1 compounds; toxic activity; PROTOCATECHUIC-ACID
  24. Alpha-Glucosidase-Inhibitor — 1 compounds; PROTOCATECHUIC-ACID
  25. Anthelmintic — 1 compounds; VANILLIC-ACID
  26. Antiallergenic — 1 compounds; toxic activity; ANDROSIN
  27. Antiarrhythmic — 1 compounds; PROTOCATECHUIC-ACID
  28. Antiarthritic — 1 compounds; APOCYNIN
  29. Antiatherosclerotic — 1 compounds; APOCYNIN
  30. Antibronchitic — 1 compounds; ANDROSIN
  31. Anticancer — 1 compounds; VANILLIC-ACID
  32. Anticlastogen — 1 compounds; PROTOCATECHUIC-ACID
  33. Anticolitic — 1 compounds; APOCYNIN
  34. Antiedemic — 1 compounds; GLUCOSE
  35. Antifatigue — 1 compounds; VANILLIC-ACID
  36. Antigibberellin — 1 compounds; CUCURBITACIN-B
  37. Antiherpetic — 1 compounds; PROTOCATECHUIC-ACID
  38. Antiischemic — 1 compounds; PROTOCATECHUIC-ACID
  39. Antiketotic — 1 compounds; GLUCOSE
  40. AntiLegionella — 1 compounds; PROTOCATECHUIC-ACID
  41. Antimelanogenic — 1 compounds; PROTOCATECHUIC-ACID
  42. Antimutagenic — 1 compounds; toxic activity; PROTOCATECHUIC-ACID
  43. Antiophidic — 1 compounds; PROTOCATECHUIC-ACID
  44. Antirheumatic — 1 compounds; APOCYNIN
  45. Antisickling — 1 compounds; VANILLIC-ACID
  46. Antispasmodic — 1 compounds; PROTOCATECHUIC-ACID
  47. Antitumor (Colon) — 1 compounds; PROTOCATECHUIC-ACID
  48. Antitumor (Mouth) — 1 compounds; PROTOCATECHUIC-ACID
  49. Antitumor (Skin) — 1 compounds; PROTOCATECHUIC-ACID
  50. Antitumor-Promoter — 1 compounds; VANILLIC-ACID
  51. Antitussive — 1 compounds; PROTOCATECHUIC-ACID
  52. Antivaricose — 1 compounds; GLUCOSE
  53. Antiviral — 1 compounds; PROTOCATECHUIC-ACID
  54. Apoptotic — 1 compounds; PROTOCATECHUIC-ACID
  55. Ascaricide — 1 compounds; VANILLIC-ACID
  56. Carcinogenic — 1 compounds; toxic activity; PROTOCATECHUIC-ACID
  57. Cardiac — 1 compounds; APOCYNIN
  58. Cardioprotective — 1 compounds; toxic activity; PROTOCATECHUIC-ACID
  59. Cartilage-Sparing — 1 compounds; APOCYNIN
  60. Cathartic — 1 compounds; CATALPOL
  61. Chemopreventive — 1 compounds; PROTOCATECHUIC-ACID
  62. Cytotoxic — 1 compounds; toxic activity; CUCURBITACIN-B
  63. Glutathione-Depleting — 1 compounds; PROTOCATECHUIC-ACID
  64. Hyperglycemic — 1 compounds; GLUCOSE
  65. Immunostimulant — 1 compounds; PROTOCATECHUIC-ACID
  66. Immunosuppressant — 1 compounds; VANILLIC-ACID
  67. Insectifuge — 1 compounds; CUCURBITACIN-B
  68. Insectiphile — 1 compounds; CUCURBITACIN-B
  69. Memory-Enhancer — 1 compounds; GLUCOSE
  70. Nephrotoxic — 1 compounds; toxic activity; PROTOCATECHUIC-ACID
  71. Phagocytotic — 1 compounds; PROTOCATECHUIC-ACID
  72. Prostaglandigenic — 1 compounds; PROTOCATECHUIC-ACID
  73. Purgative — 1 compounds; CATALPOL
  74. Secretogogue — 1 compounds; PROTOCATECHUIC-ACID
  75. Tyrosinase-Inhibitor — 1 compounds; PROTOCATECHUIC-ACID

Toxic compounds

  • ANDROSIN — Antiallergenic; Plant; 10 mg/kg
  • ANDROSIN — Antiallergenic; Root; 10 mg/kg
  • CUCURBITACIN-B — Antihepatotoxic; Root
  • CUCURBITACIN-B — Cytotoxic; Root; 2.5 ppt
  • GLUCOSE — Antihepatotoxic; Rhizome
  • PICROSIDE-I — Hepatoprotective; Root
  • PICROSIDE-I — Hepatotoxic; Root
  • PICROSIDE-II — Hepatoprotective; Rhizome
  • PICROSIDE-II — Hepatotoxic; Rhizome
  • PROTOCATECHUIC-ACID — Allergenic; Plant
  • PROTOCATECHUIC-ACID — Antihepatotoxic; Plant
  • PROTOCATECHUIC-ACID — Antimutagenic; Plant
  • PROTOCATECHUIC-ACID — Carcinogenic; Plant
  • PROTOCATECHUIC-ACID — Cardioprotective; Plant
  • PROTOCATECHUIC-ACID — Hepatotoxic; Plant
  • PROTOCATECHUIC-ACID — Nephrotoxic; Plant