Polygala senega (Seneca Snakeroot)

Traditional uses

Elsewhere

• Asthma
• Expectorant
• Poison
• Bronchitis
• Tonic

US(Amerindian)

• Bite(Snake)

US(Appalachia)

• Bite(Snake)
• Medicine

Turkey

• Diuretic
• Emetic
• Expectorant
• Sudorific
• Alterative

US

• Gout
• Hivess
• Pleurisy
• Rheumatism

US(VA)

• Cancer

Chemicals

Plant

• 1,5-ANHYDRO-(O-ALPHA-D-GALACTOPYRANOSYL-{1-2}-O-ALPHA-D-GALACTOPYRANOSYL-{1-2})
• SENEGENIC-ACID

Root

• -D-GLUCITOL
• ARABINOSYL-ALPHA-D-GALACTOSYL-D-GLUCOSE
• P-COUMARIC-ACID
• 3,4-DIMETHOXYCINNAMIC-ACID
• FERULIC-ACID
• 2-O-ALPHA-D-GALACTOPYRANOSYL-1,5-ANHYDRO-D-GLUCITOL
• GALACTOSE
• HYDROXYSENEGIN
• MANNOSE
• P-METHOXY-CINNAMIC-ACID
• METHYL-SALICYLATE — 1000
• PECTIN
• POLYGALITOL — 12000
• RAFFINOSE
• SALICYLIC-ACID-METHYL-ESTER-PRIMVEROSIDE
• SENEGENIN
• ALPHA-SPINASTEROL
• STACHYOSE
• TENUIFOLIN
• TENUIGENIN
• 3,4,5-TRIMETHOXYCINNAMIC-ACID
• XYLOSE
• GLUCOSE
• MANNINOTRIOSE
• PRESENEGIN
• RIBOSE
• SINAPIC-ACID
• ARABINOSE
• CYCLOSENEGIN
• FUCOSE
• 6-O-BETA-D-GLUCOPYRANOSYL-1,5-ANHYDRO-D-GLUCITOL
• POLYGALIC-ACID
• RHAMNOSE
• SENEGIN
• TENUIFOLIC-ACID
• VALERIANIC-ACID
• MONOTROPITOSIDE
• SAPONINS — 20000 to 100000

Activities

1. Fungicide — 6 compounds; FERULIC-ACID, METHYL-SALICYLATE, P-COUMARIC-ACID, P-METHOXY-CINNAMIC-ACID, PECTIN, SINAPIC-ACID
2. Pesticide — 6 compounds; FERULIC-ACID, METHYL-SALICYLATE, P-COUMARIC-ACID, P-METHOXY-CINNAMIC-ACID, PECTIN, SINAPIC-ACID
3. Cancer-Preventive — 5 compounds; FERULIC-ACID, METHYL-SALICYLATE, P-COUMARIC-ACID, PECTIN, SINAPIC-ACID
4. Antibacterial — 4 compounds; FERULIC-ACID, P-COUMARIC-ACID, PECTIN, SINAPIC-ACID
5. Antihepatotoxic — 4 compounds; toxic activity; FERULIC-ACID, GLUCOSE, P-COUMARIC-ACID, SINAPIC-ACID
6. Antioxidant — 4 compounds; FERULIC-ACID, METHYL-SALICYLATE, P-COUMARIC-ACID, SINAPIC-ACID
7. Antiinflammatory — 3 compounds; ALPHA-SPINASTEROL, FERULIC-ACID, METHYL-SALICYLATE
8. Antimutagenic — 3 compounds; toxic activity; FERULIC-ACID, PECTIN, SAPONINS
9. Antipyretic — 3 compounds; ALPHA-SPINASTEROL, METHYL-SALICYLATE, P-METHOXY-CINNAMIC-ACID
10. Antispasmodic — 3 compounds; FERULIC-ACID, P-COUMARIC-ACID, VALERIANIC-ACID
11. Aldose-Reductase-Inhibitor — 2 compounds; 3,4-DIMETHOXYCINNAMIC-ACID, P-COUMARIC-ACID
12. Allelopathic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
13. Analgesic — 2 compounds; FERULIC-ACID, METHYL-SALICYLATE
14. Antidiabetic — 2 compounds; PECTIN, XYLOSE
15. Antileukemic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
16. Antinitrosaminic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
17. Antiradicular — 2 compounds; FERULIC-ACID, METHYL-SALICYLATE
18. Antiseptic — 2 compounds; METHYL-SALICYLATE, P-COUMARIC-ACID
19. Antitumor — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
20. Antitumor (Colon) — 2 compounds; FERULIC-ACID, PECTIN
21. Chemopreventive — 2 compounds; P-COUMARIC-ACID, PECTIN
22. Choleretic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
23. Flatugenic — 2 compounds; RAFFINOSE, STACHYOSE
24. Hemolytic — 2 compounds; P-METHOXY-CINNAMIC-ACID, SENEGIN
25. Hypoglycemic — 2 compounds; P-METHOXY-CINNAMIC-ACID, PECTIN
26. Insectifuge — 2 compounds; FERULIC-ACID, METHYL-SALICYLATE
27. Prostaglandigenic — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
28. Prostaglandin-Synthesis-Inhibitor — 2 compounds; FERULIC-ACID, P-COUMARIC-ACID
29. Acetylcholinergic — 1 compounds; GLUCOSE
30. Allergenic — 1 compounds; toxic activity; METHYL-SALICYLATE
31. Anaphrodisiac — 1 compounds; METHYL-SALICYLATE
32. Antiadhesive — 1 compounds; MANNOSE
33. Antiaggregant — 1 compounds; FERULIC-ACID
34. Antiallergic — 1 compounds; FERULIC-ACID
35. Antiarrhythmic — 1 compounds; FERULIC-ACID
36. Antiatheromic — 1 compounds; PECTIN
37. Anticancer (Colon) — 1 compounds; FERULIC-ACID
38. Anticancer (Forestomach) — 1 compounds; FERULIC-ACID
39. Anticancer (Liver) — 1 compounds; FERULIC-ACID
40. Anticancer (Skin) — 1 compounds; FERULIC-ACID
41. Anticarcinogenic — 1 compounds; toxic activity; FERULIC-ACID
42. Anticlastogen — 1 compounds; P-COUMARIC-ACID
43. Anticystitic — 1 compounds; MANNOSE
44. Antidiarrheic — 1 compounds; PECTIN
45. Antidysmenorrheic — 1 compounds; FERULIC-ACID
46. Antiedemic — 1 compounds; GLUCOSE
47. Antienteritic — 1 compounds; PECTIN
48. Antiestrogenic — 1 compounds; FERULIC-ACID
49. Antifertility — 1 compounds; P-COUMARIC-ACID
50. Antigallstone — 1 compounds; PECTIN
51. Antigastritic — 1 compounds; PECTIN
52. Antihepatomic — 1 compounds; toxic activity; SAPONINS
53. Antiherpetic — 1 compounds; FERULIC-ACID
54. Antiketotic — 1 compounds; GLUCOSE
55. Antilithic — 1 compounds; PECTIN
56. Antimetastatic — 1 compounds; PECTIN
57. Antimitotic — 1 compounds; FERULIC-ACID
58. Antineoplastic — 1 compounds; FERULIC-ACID
59. Antiobesity — 1 compounds; PECTIN
60. Antiperoxidant — 1 compounds; P-COUMARIC-ACID
61. Antiperoxynitrite — 1 compounds; SINAPIC-ACID
62. Antirheumatalgic — 1 compounds; METHYL-SALICYLATE
63. Antiserotonin — 1 compounds; FERULIC-ACID
64. Antitartar — 1 compounds; METHYL-SALICYLATE
65. Antithrombic — 1 compounds; FERULIC-ACID
66. Antitumor (Forestomach) — 1 compounds; FERULIC-ACID
67. Antitumor (Liver) — 1 compounds; FERULIC-ACID
68. Antitumor (Lung) — 1 compounds; SAPONINS
69. Antitumor (Ovary) — 1 compounds; SAPONINS
70. Antitumor (Prostate) — 1 compounds; PECTIN
71. Antitumor (Skin) — 1 compounds; FERULIC-ACID
72. Antitumor-Promoter — 1 compounds; FERULIC-ACID
73. Antitussive — 1 compounds; PECTIN
74. Antiulcer — 1 compounds; PECTIN
75. AntiUTI — 1 compounds; MANNOSE
76. Antivaricose — 1 compounds; GLUCOSE
77. Antiviral — 1 compounds; FERULIC-ACID
78. Arteriodilator — 1 compounds; FERULIC-ACID
79. Candidicide — 1 compounds; FERULIC-ACID
80. Cardiac — 1 compounds; FERULIC-ACID
81. Carminative — 1 compounds; METHYL-SALICYLATE
82. Cholagogue — 1 compounds; FERULIC-ACID
83. Corticosterone-genic — 1 compounds; SENEGIN
84. Counterirritant — 1 compounds; toxic activity; METHYL-SALICYLATE
85. Cytotoxic — 1 compounds; toxic activity; P-COUMARIC-ACID
86. Demulcent — 1 compounds; PECTIN
87. Dentifrice — 1 compounds; METHYL-SALICYLATE
88. Diagnostic — 1 compounds; XYLOSE
89. Diaphoretic? — 1 compounds; P-COUMARIC-ACID
90. Dye — 1 compounds; XYLOSE
91. FLavor — 1 compounds; METHYL-SALICYLATE
92. Hemostat — 1 compounds; PECTIN
93. Hepatoprotective — 1 compounds; toxic activity; FERULIC-ACID
94. Hepatotropic — 1 compounds; toxic activity; FERULIC-ACID
95. Herbicide — 1 compounds; FERULIC-ACID
96. Herpetifuge — 1 compounds; METHYL-SALICYLATE
97. Hydrocholerectic — 1 compounds; FERULIC-ACID
98. Hyperglycemic — 1 compounds; GLUCOSE
99. Hypocholesterolemic — 1 compounds; PECTIN
100. Hypolipidemic — 1 compounds; FERULIC-ACID
101. Immunomodulator — 1 compounds; SAPONINS
102. Immunostimulant — 1 compounds; FERULIC-ACID
103. Insectiphile — 1 compounds; METHYL-SALICYLATE
104. Lipoxygenase-Inhibitor — 1 compounds; P-COUMARIC-ACID
105. Memory-Enhancer — 1 compounds; GLUCOSE
106. Metal-Chelator — 1 compounds; FERULIC-ACID
107. Ornithine-Decarboxylase-Inhibitor — 1 compounds; FERULIC-ACID
108. Perfumery — 1 compounds; METHYL-SALICYLATE
109. Peristaltic — 1 compounds; PECTIN
110. Phagocytotic — 1 compounds; FERULIC-ACID
111. Preservative — 1 compounds; FERULIC-ACID
112. Sunscreen — 1 compounds; FERULIC-ACID
113. Sweetener — 1 compounds; GALACTOSE
114. Tyrosinase-Inhibitor — 1 compounds; P-COUMARIC-ACID
115. Uterosedative — 1 compounds; FERULIC-ACID

Toxic compounds

• FERULIC-ACID — Anticarcinogenic; Root
• FERULIC-ACID — Antihepatotoxic; Root
• FERULIC-ACID — Antimutagenic; Root
• FERULIC-ACID — Hepatoprotective; Root
• FERULIC-ACID — Hepatotropic; Root
• GLUCOSE — Antihepatotoxic; Root
• METHYL-SALICYLATE — Allergenic; Root
• METHYL-SALICYLATE — Counterirritant; Root
• P-COUMARIC-ACID — Antihepatotoxic; Root
• P-COUMARIC-ACID — Cytotoxic; Root
• PECTIN — Antimutagenic; Root
• SAPONINS — Antihepatomic; Root
• SAPONINS — Antimutagenic; Root
• SINAPIC-ACID — Antihepatotoxic; Root