Skimmia japonica (Japanese Skimmia)

Traditional uses

China

  • Atrophy
  • Poison
  • Restorative
  • Tonic
  • Palsy
  • Cachexia

Chemicals

Leaf

  • DICTAMNINE
  • EDULIN
  • ISOIMPERATORIN — 3000
  • ISOMERANZINE
  • OXYPEUCEDANIN — 800
  • OXYPEOCEDANIN-METHANOLATE — 400
  • (+)-PLATYDESMIN
  • SESELIN
  • TARAXEROL — 1700
  • OXYPEUCEDANIN-HYDRATE — 280
  • SKIMMIANINE
  • (-)-MERANZIN-HYDRATE

Twig

  • SKIMMINE

Plant

  • FRIEDOOLEAN-14-EN-3-BETA-OL

Activities

  1. Pesticide — 4 compounds; DICTAMNINE, ISOIMPERATORIN, SESELIN, SKIMMIANINE
  2. Calcium-Antagonist — 3 compounds; ISOIMPERATORIN, OXYPEUCEDANIN, OXYPEUCEDANIN-HYDRATE
  3. Fungicide — 3 compounds; DICTAMNINE, OXYPEUCEDANIN, SESELIN
  4. Antitumor-Promoter — 2 compounds; ISOIMPERATORIN, OXYPEUCEDANIN
  5. DME-Inhibitor — 2 compounds; ISOIMPERATORIN, OXYPEUCEDANIN
  6. Phototoxic — 2 compounds; toxic activity; DICTAMNINE, SKIMMIANINE
  7. Uterocontractant — 2 compounds; DICTAMNINE, SKIMMIANINE
  8. Abortifacient — 1 compounds; toxic activity; SKIMMIANINE
  9. Adrenostimulant — 1 compounds; SKIMMIANINE
  10. Analgesic — 1 compounds; SKIMMIANINE
  11. Antiaggregant — 1 compounds; DICTAMNINE
  12. Antibacterial — 1 compounds; DICTAMNINE
  13. Anticonvulsant — 1 compounds; toxic activity; SKIMMIANINE
  14. Antidiuretic — 1 compounds; SKIMMIANINE
  15. Antihistaminic — 1 compounds; OXYPEUCEDANIN-HYDRATE
  16. Antileukemic — 1 compounds; SESELIN
  17. Antimalarial — 1 compounds; SKIMMIANINE
  18. Antipyretic — 1 compounds; SKIMMIANINE
  19. Antisecretory — 1 compounds; TARAXEROL
  20. Antispasmodic — 1 compounds; SKIMMIANINE
  21. Antiulcer — 1 compounds; TARAXEROL
  22. Antiviral — 1 compounds; DICTAMNINE
  23. Artemicide — 1 compounds; ISOIMPERATORIN
  24. Candidicide — 1 compounds; SKIMMIANINE
  25. Cardiotonic — 1 compounds; toxic activity; DICTAMNINE
  26. CNS-Depressant — 1 compounds; SKIMMIANINE
  27. CNS-Stimulant — 1 compounds; SKIMMIANINE
  28. Cytochrome-P450-Inhibitor — 1 compounds; ISOIMPERATORIN
  29. Cytotoxic (Breast) — 1 compounds; toxic activity; ISOIMPERATORIN
  30. Cytotoxic (Colon) — 1 compounds; toxic activity; ISOIMPERATORIN
  31. DNA-Binder — 1 compounds; DICTAMNINE
  32. Ecbolic — 1 compounds; SKIMMIANINE
  33. Hypertensive — 1 compounds; SKIMMIANINE
  34. Hypothermic — 1 compounds; SKIMMIANINE
  35. Lipolytic — 1 compounds; OXYPEUCEDANIN
  36. Mutagenic — 1 compounds; toxic activity; OXYPEUCEDANIN
  37. Myocontractant — 1 compounds; DICTAMNINE
  38. Myorelaxant — 1 compounds; SKIMMIANINE
  39. Myotonic — 1 compounds; SKIMMIANINE
  40. Photoactive — 1 compounds; DICTAMNINE
  41. Sedative — 1 compounds; SKIMMIANINE
  42. Vasodilator — 1 compounds; SKIMMIANINE

Toxic compounds

  • DICTAMNINE — Cardiotonic; Leaf
  • DICTAMNINE — Phototoxic; Leaf
  • ISOIMPERATORIN — Cytotoxic (Breast); Leaf; ED50=6.56 ug/ml
  • ISOIMPERATORIN — Cytotoxic (Colon); Leaf; ED50=>10 ug/ml
  • OXYPEUCEDANIN — Mutagenic; Leaf
  • SKIMMIANINE — Abortifacient; Leaf
  • SKIMMIANINE — Anticonvulsant; Leaf
  • SKIMMIANINE — Phototoxic; Leaf