Stephania glabra (Indian Tape-Vine)

Traditional uses

India

  • Ache(Body)
  • Ache(Head)
  • Eye
  • Massage

Elsewhere

  • Antibiotic
  • Asthma
  • Convulsion
  • Hyperglycemia
  • Inflammation
  • Sedative
  • Intestine
  • Tuberculosis

Chemicals

Root

  • ALKALOIDS — 60000 to 75000
  • CYCLEANINE
  • DEHYDROCORYDALMINE
  • GINDARINE
  • GINDARININE
  • MAGNOFLORINE
  • N-METHYLHYDOXYSTEPHARINE
  • STEPHARANINE
  • STEPHARINE
  • TETRAHYDROPALMATINE
  • JATRORRHIZINE
  • N-METHYLOXYSTEPHANINE
  • COLUMBAMINE
  • GINDARICINE
  • HYNDARINE
  • PALMATINE
  • ROTUNDINE
  • STEPHARARINE
  • (-)-STEPHOLIDINE

Stem

  • ALKALOIDS — 10000

Plant

  • (+)-PRONUCIFERINE
  • REMERINE
  • N-DEMETHYCYCLEANINE
  • (-)-CORYDALMINE

Activities

  1. Hypotensive — 5 compounds; COLUMBAMINE, CYCLEANINE, JATRORRHIZINE, MAGNOFLORINE, PALMATINE
  2. Analgesic — 4 compounds; CYCLEANINE, PALMATINE, ROTUNDINE, TETRAHYDROPALMATINE
  3. Antimalarial — 4 compounds; (-)-CORYDALMINE, COLUMBAMINE, JATRORRHIZINE, PALMATINE
  4. CNS-Depressant — 4 compounds; COLUMBAMINE, JATRORRHIZINE, MAGNOFLORINE, PALMATINE
  5. Pesticide — 4 compounds; COLUMBAMINE, JATRORRHIZINE, MAGNOFLORINE, PALMATINE
  6. Antibacterial — 3 compounds; COLUMBAMINE, MAGNOFLORINE, PALMATINE
  7. Antiinflammatory — 3 compounds; CYCLEANINE, JATRORRHIZINE, PALMATINE
  8. Sedative — 3 compounds; JATRORRHIZINE, ROTUNDINE, TETRAHYDROPALMATINE
  9. Antiarrhythmic — 2 compounds; PALMATINE, TETRAHYDROPALMATINE
  10. Antiplasmodial — 2 compounds; (-)-CORYDALMINE, JATRORRHIZINE
  11. Antipyretic — 2 compounds; CYCLEANINE, PALMATINE
  12. Antisilicotic — 2 compounds; CYCLEANINE, TETRAHYDROPALMATINE
  13. Calcium-Antagonist — 2 compounds; (-)-STEPHOLIDINE, TETRAHYDROPALMATINE
  14. Enterotonic — 2 compounds; COLUMBAMINE, JATRORRHIZINE
  15. Protisticide — 2 compounds; CYCLEANINE, JATRORRHIZINE
  16. Tranquilizer — 2 compounds; ROTUNDINE, TETRAHYDROPALMATINE
  17. Abortifacient — 1 compounds; toxic activity; PALMATINE
  18. Adrenocorticotrophic — 1 compounds; PALMATINE
  19. Antiaggregant — 1 compounds; CYCLEANINE
  20. Antialopecic — 1 compounds; CYCLEANINE
  21. Antialzheimeran? — 1 compounds; PALMATINE
  22. Antiarthritic — 1 compounds; CYCLEANINE
  23. Anticholinesterase — 1 compounds; PALMATINE
  24. Antidandruff — 1 compounds; CYCLEANINE
  25. Antiinfarctal — 1 compounds; PALMATINE
  26. Antileishmanic — 1 compounds; CYCLEANINE
  27. Antineuromuscular — 1 compounds; toxic activity; MAGNOFLORINE
  28. Antiphotooxidative — 1 compounds; JATRORRHIZINE
  29. Antispasmodic — 1 compounds; MAGNOFLORINE
  30. Antitumor — 1 compounds; CYCLEANINE
  31. Choleretic — 1 compounds; COLUMBAMINE
  32. CNS-Stimulant — 1 compounds; JATRORRHIZINE
  33. Curaroid — 1 compounds; MAGNOFLORINE
  34. Cytotoxic — 1 compounds; toxic activity; CYCLEANINE
  35. Dopamine-Receptor-Inhibitor — 1 compounds; CYCLEANINE
  36. Fungicide — 1 compounds; JATRORRHIZINE
  37. Ganglionic-Blocker — 1 compounds; CYCLEANINE
  38. Hepatoprotective — 1 compounds; toxic activity; CYCLEANINE
  39. Hypnotic — 1 compounds; TETRAHYDROPALMATINE
  40. Hypotensive? — 1 compounds; TETRAHYDROPALMATINE
  41. Inotropic — 1 compounds; PALMATINE
  42. Myorelaxant — 1 compounds; CYCLEANINE
  43. PAF-Inhibitor — 1 compounds; MAGNOFLORINE
  44. Paralytic — 1 compounds; toxic activity; MAGNOFLORINE
  45. Respiradepressant — 1 compounds; PALMATINE
  46. Toxic — 1 compounds; toxic activity; MAGNOFLORINE
  47. Uterocontractant — 1 compounds; JATRORRHIZINE
  48. Uterotonic — 1 compounds; PALMATINE
  49. Vasodilator — 1 compounds; MAGNOFLORINE

Toxic compounds

  • CYCLEANINE — Cytotoxic; Root; 12 ppm
  • CYCLEANINE — Hepatoprotective; Root; 10 mg/kg
  • MAGNOFLORINE — Antineuromuscular; Root; ED50=10 mg/kg
  • MAGNOFLORINE — Paralytic; Root
  • MAGNOFLORINE — Toxic; Root
  • PALMATINE — Abortifacient; Root