Xylopia aethiopica (Ethiopian Pepper)

Traditional uses

Ghana

  • Ache(Head)
  • Cough
  • Neuralgia
  • Purgative
  • Rheumatism
  • Sore
  • Emetic
  • Carminative
  • Emmenagogue
  • Stimulant

Africa

  • Bilious
  • Bronchitis
  • Eruption
  • Vermifuge
  • Dysentery
  • Fertility(Female)
  • Boil
  • Lumbago

Liberia

  • Fumitory
  • Respiratory

Nigeria

  • Cancer

Chemicals

Fruit

  • ANONACEIN
  • CINEOLE — 1260 to 1560
  • EO — 20000
  • FAT — 128800 to 345000
  • (-)-15-HYDROXY-KAUR-16-ENIC-ACID
  • (-)-KAUR-16-ENIC-ACID
  • (-)-KAURAN-16-ALPHA-19-DIOL
  • (-)-KAURAN-16-ALPHA-OL
  • (-)-15-OXOKAUR-16-ENIC-ACID
  • RESIN
  • RUTIN

Seed

  • CELLULOSE — 295500
  • CINEOLE — 815 to 1015
  • CUMINAL
  • EO — 13000
  • GLUCOSE — 10900
  • PIPERINE — 9100
  • XYLOPIC-ACID — 13000

Leaf

  • CREBANINE — 2.3
  • LANUGINOSINE — 2.7
  • LIRIODENINE — 1.1
  • OXOCREBANINE — 1.7
  • ROEMERINE — 4.1
  • STEPANININE — 1.8

Activities

  1. Antibacterial — 3 compounds; LIRIODENINE, PIPERINE, RUTIN
  2. Antiedemic — 3 compounds; GLUCOSE, PIPERINE, RUTIN
  3. Pesticide — 3 compounds; LIRIODENINE, PIPERINE, RUTIN
  4. Analgesic — 2 compounds; LIRIODENINE, PIPERINE
  5. Anticlastogen — 2 compounds; PIPERINE, RUTIN
  6. Anticonvulsant — 2 compounds; toxic activity; PIPERINE, RUTIN
  7. Antihepatotoxic — 2 compounds; toxic activity; GLUCOSE, RUTIN
  8. Antiinflammatory — 2 compounds; PIPERINE, RUTIN
  9. Antimutagenic — 2 compounds; toxic activity; PIPERINE, RUTIN
  10. Antinociceptive — 2 compounds; PIPERINE, RUTIN
  11. Antioxidant — 2 compounds; PIPERINE, RUTIN
  12. Antispasmodic — 2 compounds; PIPERINE, RUTIN
  13. Antitumor — 2 compounds; LIRIODENINE, RUTIN
  14. Antivaricose — 2 compounds; GLUCOSE, RUTIN
  15. Cancer-Preventive — 2 compounds; PIPERINE, RUTIN
  16. Hemostat — 2 compounds; CELLULOSE, RUTIN
  17. Hepatoprotective — 2 compounds; toxic activity; PIPERINE, RUTIN
  18. Hypotensive — 2 compounds; PIPERINE, RUTIN
  19. Insecticide — 2 compounds; PIPERINE, RUTIN
  20. Mutagenic — 2 compounds; toxic activity; PIPERINE, RUTIN
  21. Myorelaxant — 2 compounds; PIPERINE, RUTIN
  22. Topoisomerase-II-Inhibitor — 2 compounds; LIRIODENINE, RUTIN
  23. Vasodilator — 2 compounds; LIRIODENINE, RUTIN
  24. 5-HT-Inhibitor — 1 compounds; RUTIN
  25. Abortifacient — 1 compounds; toxic activity; PIPERINE
  26. Acetylcholinergic — 1 compounds; GLUCOSE
  27. Adrenergic — 1 compounds; PIPERINE
  28. AHH-Inhibitor — 1 compounds; PIPERINE
  29. Aldehyde-Oxidase-Inhibitor — 1 compounds; RUTIN
  30. Aldose-Reductase-Inhibitor — 1 compounds; RUTIN
  31. Allelochemic — 1 compounds; RUTIN
  32. Analeptic — 1 compounds; PIPERINE
  33. Anesthetic — 1 compounds; PIPERINE
  34. Antiaflatoxin — 1 compounds; PIPERINE
  35. Antiaggregant — 1 compounds; RUTIN
  36. Antiallergic — 1 compounds; RUTIN
  37. Antiapoplectic — 1 compounds; RUTIN
  38. Antiatherogenic — 1 compounds; RUTIN
  39. Antiatherosclerotic — 1 compounds; RUTIN
  40. Anticancer — 1 compounds; RUTIN
  41. Anticapillary-Fragility — 1 compounds; RUTIN
  42. Anticataract — 1 compounds; RUTIN
  43. AntiCVI — 1 compounds; RUTIN
  44. Antidementia — 1 compounds; RUTIN
  45. Antidermatitic — 1 compounds; toxic activity; RUTIN
  46. Antidermatophytic — 1 compounds; LIRIODENINE
  47. Antidiabetic — 1 compounds; RUTIN
  48. Antierythemic — 1 compounds; RUTIN
  49. Antifeedant — 1 compounds; RUTIN
  50. Antifertility — 1 compounds; PIPERINE
  51. Antiglaucomic — 1 compounds; RUTIN
  52. Antiglucuronidase — 1 compounds; PIPERINE
  53. Antihematuric — 1 compounds; RUTIN
  54. Antihemorrhoidal — 1 compounds; RUTIN
  55. Antiherpetic — 1 compounds; RUTIN
  56. Antihistaminic — 1 compounds; RUTIN
  57. Antihypertensive — 1 compounds; RUTIN
  58. Antiimplantation — 1 compounds; PIPERINE
  59. Antiketotic — 1 compounds; GLUCOSE
  60. Antileishmanic — 1 compounds; PIPERINE
  61. Antimalarial — 1 compounds; RUTIN
  62. Antimelanomic — 1 compounds; RUTIN
  63. Antimetastatic — 1 compounds; RUTIN
  64. Antinarcotic — 1 compounds; toxic activity; PIPERINE
  65. Antinephritic — 1 compounds; RUTIN
  66. Antiperoxidant — 1 compounds; RUTIN
  67. Antiplasmodial — 1 compounds; PIPERINE
  68. Antiplatelet — 1 compounds; RUTIN
  69. Antiproliferant — 1 compounds; RUTIN
  70. Antiprotozoal — 1 compounds; RUTIN
  71. Antipurpuric — 1 compounds; RUTIN
  72. Antipyretic — 1 compounds; PIPERINE
  73. Antiradicular — 1 compounds; RUTIN
  74. Antiseptic — 1 compounds; PIPERINE
  75. AntiSubstance-P — 1 compounds; PIPERINE
  76. Antisunburn — 1 compounds; RUTIN
  77. Antithrombogenic — 1 compounds; RUTIN
  78. Antithyroid — 1 compounds; RUTIN
  79. Antitrypanosomic — 1 compounds; RUTIN
  80. Antitumor-Promoter — 1 compounds; RUTIN
  81. Antiulcer — 1 compounds; RUTIN
  82. Antiviral — 1 compounds; RUTIN
  83. Apoptotic — 1 compounds; RUTIN
  84. Aryl-Hydrocarbon-Hydroxylase-Inhibitor — 1 compounds; PIPERINE
  85. ATPase-Stimulant — 1 compounds; PIPERINE
  86. cAMP-Phosphodiesterase-Inhibitor — 1 compounds; RUTIN
  87. Candidicide — 1 compounds; LIRIODENINE
  88. Capillariprotective — 1 compounds; RUTIN
  89. Carcinogenic — 1 compounds; toxic activity; PIPERINE
  90. Cardiotonic — 1 compounds; toxic activity; PIPERINE
  91. Carminative — 1 compounds; PIPERINE
  92. Catabolic — 1 compounds; RUTIN
  93. Catecholaminogenic — 1 compounds; PIPERINE
  94. Chemopreventive — 1 compounds; RUTIN
  95. CNS-Stimulant — 1 compounds; PIPERINE
  96. Cytoprotective — 1 compounds; RUTIN
  97. Cytotoxic — 1 compounds; toxic activity; LIRIODENINE
  98. Diaphoretic — 1 compounds; PIPERINE
  99. Endorphinogenic — 1 compounds; PIPERINE
  100. Epinephrininergic — 1 compounds; PIPERINE
  101. Estrogenic? — 1 compounds; RUTIN
  102. FLavor — 1 compounds; PIPERINE
  103. Fungicide — 1 compounds; LIRIODENINE
  104. Hepatomagenic — 1 compounds; toxic activity; RUTIN
  105. Hepatoregenerative — 1 compounds; toxic activity; PIPERINE
  106. Hyperglycemic — 1 compounds; GLUCOSE
  107. Hypertensive — 1 compounds; PIPERINE
  108. Hypocholesterolemic — 1 compounds; RUTIN
  109. Immunomodulator — 1 compounds; RUTIN
  110. Insectifuge — 1 compounds; PIPERINE
  111. Insectiphile — 1 compounds; RUTIN
  112. Juvabional — 1 compounds; RUTIN
  113. Larvistat — 1 compounds; RUTIN
  114. Lipoxygenase-Inhibitor — 1 compounds; RUTIN
  115. Memory-Enhancer — 1 compounds; GLUCOSE
  116. Myocontractant — 1 compounds; PIPERINE
  117. Myoprotective — 1 compounds; RUTIN
  118. Oviposition-Stimulant — 1 compounds; RUTIN
  119. P450-Inducer — 1 compounds; PIPERINE
  120. P450-Inhibitor — 1 compounds; PIPERINE
  121. PAF-Inhibitor — 1 compounds; RUTIN
  122. Parasiticide — 1 compounds; PIPERINE
  123. Peristaltic — 1 compounds; PIPERINE
  124. Protisticide — 1 compounds; RUTIN
  125. Radioprotective — 1 compounds; RUTIN
  126. Respirostimulant — 1 compounds; PIPERINE
  127. Secretogogue — 1 compounds; PIPERINE
  128. Sedative — 1 compounds; LIRIODENINE
  129. Serotoninergic — 1 compounds; PIPERINE
  130. Spermigenic — 1 compounds; PIPERINE
  131. Stimulant — 1 compounds; PIPERINE
  132. Sunscreen — 1 compounds; RUTIN
  133. Thermogenic — 1 compounds; PIPERINE
  134. Thyrostimulant — 1 compounds; PIPERINE
  135. Vasopressor — 1 compounds; RUTIN

Toxic compounds

  • GLUCOSE — Antihepatotoxic; Seed
  • LIRIODENINE — Cytotoxic; Leaf
  • PIPERINE — Abortifacient; Seed
  • PIPERINE — Anticonvulsant; Seed; 50-400 mg/kg ipr
  • PIPERINE — Antimutagenic; Seed
  • PIPERINE — Antinarcotic; Seed
  • PIPERINE — Carcinogenic; Seed
  • PIPERINE — Cardiotonic; Seed
  • PIPERINE — Hepatoprotective; Seed
  • PIPERINE — Hepatoregenerative; Seed
  • PIPERINE — Mutagenic; Seed
  • RUTIN — Anticonvulsant; Fruit
  • RUTIN — Antidermatitic; Fruit
  • RUTIN — Antihepatotoxic; Fruit
  • RUTIN — Antimutagenic; Fruit; ID50=2-5 nM
  • RUTIN — Hepatomagenic; Fruit; 20,000 ppm (diet) rat
  • RUTIN — Hepatoprotective; Fruit; 20 mg/kg rat
  • RUTIN — Mutagenic; Fruit